Ann Clin Microbiol.  2019 Sep;22(3):55-60. 10.5145/ACM.2019.22.3.55.

Serotyping and Antimicrobial Susceptibility of Salmonella Isolated in Korea in 2015

• Kim SH
• Park EH
• Hwang IY
• Lee H
• Song SA
• Lee M
• Lee S
• Kim SY
• Kim JJ
• Shin JH
• Hong SG
• Shin KS
• Kim S
• Ryoo NH
• Lee W
• Jang SJ
• Shin JH

• KMID: 2459176
• DOI: http://doi.org/10.5145/ACM.2019.22.3.55

Abstract

BACKGROUND
Salmonella is an important pathogen that causes gastroenteritis and sepsis in humans. Recently, changes in serotype prevalence and an increase in antimicrobial resistance have been reported. This study investigated the distribution of Salmonella serotypes and determined the antimicrobial susceptibility of various strains.
METHODS
We collected 113 Salmonella isolates other than Salmonella serotype Typhi from 18 university hospitals in 2015. The serotypes were identified by Salmonella antisera O and H according to the Kauffman White scheme. Antimicrobial susceptibility tests for 12 antibiotics were performed using the disk diffusion method or E-test.
RESULTS
We identified 22 serotypes. Serotype group B (44.2%) was the most common, followed by groups C (34.5%) and D (21.2%). Salmonella I 4,[5],12:i:- (23.0%), S. Enteritidis (16.8%), and S. Typhimurium (12.4%) were the most common species. Resistance rates for ampicillin, chloramphenicol, ceftriaxone, and trimethoprim/sulfamethoxazole were 46.9%, 18.5%, 8.8%, and 5.3%, respectively. The intermediate resistance rate to ciprofloxacin was 29.2%. Six isolates were extended-spectrum β-lactamase (ESBL) producers, including 5 bla(CTX-M-15) and 1 bla(CTX-M-55).
CONCLUSION
There have been changes in the serotype prevalence and antimicrobial resistance of Salmonella in Korea, with a high prevalence of CTX-M 15-positive strains. Continuous monitoring of Salmonella serotypes and antimicrobial resistance is warranted.

Keyword

Antimicrobial resistance; Salmonella; Serotype

MeSH Terms

Ampicillin
Anti-Bacterial Agents
Ceftriaxone
Chloramphenicol
Ciprofloxacin
Diffusion
Gastroenteritis
Hospitals, University
Humans
Immune Sera
Korea*
Methods
Prevalence
Salmonella*
Sepsis
Serogroup
Serotyping*
Ampicillin
Anti-Bacterial Agents
Ceftriaxone
Chloramphenicol
Ciprofloxacin
Immune Sera

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