J Korean Soc Radiol.  2019 Jul;80(4):804-809. 10.3348/jksr.2019.80.4.804.

Desmoid-Type Fibromatosis Associated with Silicone Breast Implants

• Park JS
• Lee SE
• Choi JH

• KMID: 2457462
• DOI: http://doi.org/10.3348/jksr.2019.80.4.804

Abstract

Desmoid-type fibromatosis (extra-abdominal desmoid tumor) arising in the breast is a rare benign disease entity, accounting for 0.2% of all breast tumors. The etiology of mammary fibromatosis is unknown, but has been reported to be associated with genetic factors, hormonal effects, Gardner syndrome, breast trauma or surgery, and breast implants. Fibromatosis associated with breast implants is extremely rare, and only 34 cases have been reported so far. We report the ultrasonographic, computed tomographic, and pathologic findings of breast fibromatosis in a 29-year-old woman, who underwent bilateral augmentation mammoplasty with silicone implants.

MeSH Terms

Adult
Breast Implants*
Breast Neoplasms
Breast*
Female
Fibroma*
Fibromatosis, Aggressive
Gardner Syndrome
Humans
Mammaplasty
Silicon*
Silicones*
Ultrasonography
Silicon
Silicones

Figure

• 

  Fig. 1 Radiologic and pathologic findings of desmoid-type fibromatosis associated with silicone breast implants in a 29-year-old woman. A. Ultrasonography images show an oval-shaped, circumscribed marginated heterogeneous hypoechoic mass beneath the pectoralis major muscle of the right breast. The lesion is classified as BI-RADS category 4A based on ultrasound image findings. B. Color Doppler study shows internal vascularity within the mass. C–E. Axial (C), sagittal (D), and coronal (E) images obtained with contrast-enhanced CT of the chest reveal a well-defined oval-shaped mass, measuring 10.5 × 6.5 × 6.0 cm, that is in direct contact with the inferomedial aspect of the right breast implant. The mass extends to the thorax with chest wall invasion and indentation of the adjacent pleura (arrowheads). The mass shows spindle-shaped margins with a characteristic linear tail (arrows) extending along the fascial plane of the chest wall. Small amounts of fluid collection (*) can be observed in the capsule between the mass and implant. F. Gross specimen (left panel) demonstrates a well-defined yellowish- to gray-colored mass measuring 10.0 × 6.5 × 6.0 cm. Microscopic findings (middle panel) demonstrate spindle-shaped tumor cells arranged in a long fascicular pattern (hematoxylin and eosin stain, × 200). The tumor cells show nuclear staining for β-catenin (immunohistochemical stain × 200) (right panel). BI-RADS = Breast Imaging Reporting and Data System

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