J Bone Metab.  2019 Aug;26(3):161-167. 10.11005/jbm.2019.26.3.161.

Association between Colorectal Adenoma and Hand Grip Strength in the Elderly

Affiliations
  • 1Department of Family Medicine, Jeju National University Hospital, Jeju, Korea. fmhjukim@hanmail.net
  • 2Department of Family Medicine, Jeju National University School of Medicine, Jeju, Korea.
  • 3Jeju National University School of Medicine, Jeju, Korea.

Abstract

BACKGROUND
Obesity is known as an important risk factor for colorectal adenoma. However, for the elderly with changes in body composition, reduced muscle, and increased fat, the body mass index (BMI), one of the most commonly used indicators of obesity, is limited in predicting a link to colorectal cancer. This study aimed to investigate the relationship between colorectal adenoma and grip strength that can predict muscle reduction in the elderly.
METHODS
This study included 262 participants aged ≥65 years who underwent medical examination between June 2015 and August 2018. The control group comprised participants with normal findings or hyperplasia and other benign lesions, except adenoma on colonoscopy, whereas the adenoma group consisted of participants with more than one adenoma. Grip strength was alternately measured twice for each hand using a hydraulic dynamometer.
RESULTS
The grip strength was statistically lower in the adenoma group than in the control group among women (P=0.042). For both sexes, grip strength was significantly lower in participants with ≥5 adenomas than in those with <5 adenomas (P=0.021, P=0.007). Similarly, men with large adenomas (≥7 mm) exhibited significantly lower grip strength than did those with small adenomas (<7 mm) (P=0.004). Even after correction for age, BMI, smoking status, alcohol consumption, exercise, insulin resistance, hypertension, and diabetes, the negative correlation between grip strength and number of adenomas among men and women remained (P=0.034, P=0.019).
CONCLUSIONS
A significant relationship between hand grip strength and number of colorectal adenomas was noted.

Keyword

Adenoma; Aged; Body composition; Hand strength

MeSH Terms

Adenoma*
Aged*
Alcohol Drinking
Body Composition
Body Mass Index
Colonoscopy
Colorectal Neoplasms
Female
Hand Strength*
Hand*
Humans
Hyperplasia
Hypertension
Insulin Resistance
Male
Obesity
Risk Factors
Smoke
Smoking
Smoke

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