Clin Psychopharmacol Neurosci.  2019 Mar;17(2):323-325. 10.9758/cpn.2019.17.2.323.

Comorbid Zolpidem Dependence and Over-the-Counter Compound Analgesic Abuse

  • 1Department of Psychiatry, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Korea.


Zolpidem is a commonly prescribed hypnotic used to treat insomnia. However, its potential for abuse and dependence has recently become controversial. Although over-the-counter (OTC) medications are widely used, their abuse potential has not received much research attention. We report a case of comorbid zolpidem and OTC compound analgesic abuse. OTC analgesics may serve as gateway drugs, and physicians must be cautious about this issue, especially when prescribing hypnotics or benzodiazepines.


Zolpidem; Dependence; Over the counter drugs; Abuse
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