Clin Psychopharmacol Neurosci.
2019 Mar;17(2):183-188. 10.9758/cpn.2019.17.2.183.
Posttraumatic Embitterment Disorder in Patients with Chronic Kidney Disease
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. drkimyk@catholic.ac.kr
- 2Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. pae@catholic.ac.kr
- 3Department of Psychiatry and Behavioral Sciences, Duke Medical Center, Durham, NC, USA.
- 4Cell Death Disease Research Center, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- KMID: 2456721
- DOI: http://doi.org/10.9758/cpn.2019.17.2.183
Abstract
OBJECTIVE
Posttraumatic embitterment disorder (PTED), a subgroup of an adjustment disorder, is a feeling with anger and helplessness. Hemodialysis may be a trigger event leading to PTED. We investigated the prevalence of PTED in patients with each categorized stages of chronic kidney disease (CKD) and the association between PTED and depression and functional impairment.
METHODS
Patients were categorized into three groups according to the stages of CKD (stage I-II, III-IV, and V). CKD (I-II) group was defined as estimated glomerular filtration rate (eGFR) >60 ml/min/1.73 m², CKD (III-IV) group as eGFR <60 ml/min/1.73 m², and CKD (V) group as CKD stage V including patients ongoing hemodialysis. Patients were assessed for the prevalence of PTED, depression, and decreased quality of life by using the scale of PTED, Patient Health Questionnaire-9 (PHQ-9), and EuroQol Five Dimensional Questionnaires, Visual Analogue Scale (EQ-5D-VAS), respectively.
RESULTS
A total of 445 patients were analyzed. The number of patients in CKD (I-II) was 166, CKD (III-IV) was 172, and CKD (V) was 107. Multivariate analysis by binomial logistic regression demonstrated that CKD (V) was significantly associated with the prevalence of PTED (odds ratio, 4.13; 95% confidence interval, 1.56-15.6; p=0.006) after adjustment for age, gender, and diabetes mellitus. Also, a significant correlation existed between PTED and EQ-5D-VAS in all stages, but the correlation was nonsignificant between PTED and PHQ-9 score in group CKD (V).
CONCLUSION
The findings suggest that PTED is underdiagnosed in CKD patients. Acknowledgment and diagnosis of PTED in CKD patients may lead to a better quality of life.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Embitterment in Vietnam War Veterans Predicted by Symptoms of Posttraumatic Stress Disorder
- Factors Influencing Posttraumatic Stress Disorder Symptoms in Burn Injured Patients: Embitterment, Depression and Meaning in Life
- Standardization of the Korean Version of the Posttraumatic Embitterment Disorder Self-Rating Scale
- The Relationship Between Posttraumatic Embitterment Disorder and Stress, Depression, Self-Esteem, Impulsiveness, and Suicidal Ideation in Korea Soldiers in the Local Area
- Social Support as a Mediator of Posttraumatic Embitterment and Perceptions of Meaning in Life among Danwon Survivors of the Sewol Ferry Disaster
