J Korean Orthop Assoc.  1980 Sep;15(3):588-591. 10.4055/jkoa.1980.15.3.588.

Malignant Fibrous Histiocytoma: A Case report

Abstract

A case of malignant fibrous histiocytoma in the right thigh is reported together with a brief review of literature in this paper. This tumor characteristically consists of a solitary circumscribed and firm mass 5 × 5 × 4cm in dimension, which has originated in the deep soft tissues. Wide local excision has been the most common form of treatment for this lesion, after open biopsy has been performed for the diagnosis. Microscopically, there is a pattern of histiocytes and bizarre histiocytic giant cells intermingled in a fibrous stroma with fibroblasts arranged in storiform pattern. Foam cells and abnormal mitoses are also frequently found in this tumor. Local recurrence is common. Metastasis is less common but with metastasis the prognosis is poor. In this case local recurrence was noted two months after excisional biopsy but metastasis was not occurred.

Keyword

Mailgnant Fibrous Histiocytoma of Lower Extremity.

MeSH Terms

Biopsy
Diagnosis
Fibroblasts
Foam Cells
Giant Cells
Histiocytes
Histiocytoma, Malignant Fibrous*
Mitosis
Neoplasm Metastasis
Prognosis
Recurrence
Thigh
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