Ann Hepatobiliary Pancreat Surg.  2019 Aug;23(3):274-277. 10.14701/ahbps.2019.23.3.274.

Inferior vena cava leiomyosarcoma in an octogenerian

Affiliations
  • 1Department of General Surgery, Tan Tock Seng Hospital, Singapore. vishal_g_shelat@ttsh.com.sg

Abstract

Inferior Vena Cava (IVC) leiomyosarcoma (LM) is a rare malignancy of mesenchymal origin with an incidence of 1/100,000. We present an 82-year-old lady with a past history of open cholecystectomy who presented with a large indeterminate mass on abdominal imaging. Open resection of the mass was performed and histology with immunohistochemical staining revealed leiomyosarcoma. She received adjuvant radiotherapy and remained disease free 4 years after.

Keyword

Inferior vena cava; Leiomyosarcoma; Octogenerian; Sarcoma; Vascular tumour

MeSH Terms

Aged, 80 and over
Cholecystectomy
Humans
Incidence
Leiomyosarcoma*
Radiotherapy, Adjuvant
Sarcoma
Vena Cava, Inferior*

Figure

  • Fig. 1 Preoperative computed tomography of the abdomen and pelvis. Computed tomography scan showing mass with internal calcification which abuts inferior vena cava and is within the gallbladder bed.

  • Fig. 2 Histopathological specimens of the tumor. (A) Macroscopic photos of resection specimen showing the characteristic fleshy appearance of a mesenchymal tumor. (B) intersecting fascicles of eosinophilic tumor cells (Haematoxylin and eosin stain ×50). (C) Areas show marked nuclear atypia with mitoses (Haematoxylin and eosin ×200). (D) The tumor cells show strong desmin positivity (Desmin stain ×200).


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