J Korean Soc Laryngol Phoniatr Logoped.  2019 Jun;30(1):61-64. 10.0000/jkslpl.2019.30.1.61.

A Case of Unilateral Vocal Fold Paralysis Secondary to Sarcoidosis

• Lee OH
• Bang J
• Lee D
• Cho JH

• KMID: 2452817
• DOI: http://doi.org/10.0000/jkslpl.2019.30.1.61

Abstract

Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Vocal fold paralysis secondary to sarcoidosis is extremely rare but it can develop as a result of compressive lymphadenopathy, granulomatous infiltration, and neural involvement. We report the case of a 56-year-old woman who presented with unilateral vocal fold paralysis and enlarged supraclavicular lymph nodes. Computed tomography of the neck revealed multiple, enlarged, and matted lymph nodes at the cervical level of IV. An ultrasound-guided core needle biopsy of the lymph node was performed, and a histopathological diagnosis of sarcoidosis was made by validating the presence of noncaseating granuloma. After implementation of steroid therapy, the patient exhibited immediate recovery from vocal fold paralysis. Although an extremely rare disease, sarcoidosis should be included in the differential diagnosis of vocal fold paralysis. Accurate diagnosis and prompt steroid treatment may reduce the morbidity of patients with vocal fold paralysis secondary to sarcoidosis.

Keyword

Sarcoidosis; Vocal fold paralysis; Lymphadenopathy; Steroid

MeSH Terms

Biopsy, Large-Core Needle
Diagnosis
Diagnosis, Differential
Female
Granuloma
Humans
Lymph Nodes
Lymphatic Diseases
Middle Aged
Neck
Paralysis*
Rare Diseases
Sarcoidosis*
Vocal Cords*