Investig Clin Urol.  2019 Jul;60(4):267-274. 10.4111/icu.2019.60.4.267.

Classification of nocturia by analyzing frequency volume chart and relations with international prostate symptom score in male patients with lower urinary tract symptoms in Korea

• Choi YS
• Kim JC
• Kim YH
• Choi JB
• Park WH
• Lee DH

• KMID: 2450544
• DOI: http://doi.org/10.4111/icu.2019.60.4.267

Abstract

PURPOSE
To evaluate the categories of nocturia and relationships with the international prostate symptom score (IPSS) in Korean men with lower urinary tract symptoms (LUTS) accompanying nocturia.
MATERIALS AND METHODS
Five hundred twenty-one male patients from five different hospitals, aged ≥18 years, were included. The 3-day frequency volume chart was used to identify nocturia. We also used the IPSS and The International Consultation on Incontinence Modular Questionnaire-Nocturia (ICIQ-N) module to verify the correlation between nocturia and quality of life.
RESULTS
The distribution of nocturia events varied from 1 to 11, and 2 nocturia events were most prevalent (48.4%). Across the various numbers of nocturia events, the mean age, first sleep period, functional bladder capacity (FBC), nocturnal polyuria index (NPI), nocturia index (NI), predicted number of nightly voids, and nocturnal bladder capacity index (NBCI) were statistically different. Patients with pure nocturnal polyuria showed different night lengths, nocturnal urine volume, FBC, NPI, NI, and predicted number of nightly voids than those without nocturnal polyuria. Patients with severely reduced NBCI were prominent in the IPSS >20 group, and the degree of vexation increased with the number of nocturia events. The IPSS storage symptom score and ICIQ-N symptom score positively correlated with nocturia events.
CONCLUSIONS
In Korean male LUTS patients with nocturia, mixed-type nocturia was prominent, and patients with a high IPSS had a much poorer sleep quality than those with a low IPSS.

Keyword

Lower urinary tract symptoms; Nocturia; Prostate; Surveys and questionnaires

MeSH Terms

Classification*
Humans
Korea*
Lower Urinary Tract Symptoms*
Male*
Nocturia*
Polyuria
Prostate*
Quality of Life
Surveys and Questionnaires
Urinary Bladder

Figure

• 

  Fig. 1 Distribution of nocturia episodes of 521 patients. The distribution of nocturia episode varies from 1 to 11. The most prevalent episode is 2 (48.4%), and 1 (25.7%), 3 (18.4%), 4 events (5.4%) respectively.

Reference

1. van Kerrebroeck P, Abrams P, Chaikin D, Donovan J, Fonda D, Jackson S, et al. The standardisation of terminology in nocturia: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn. 2002; 21:179–183. PMID: 11857672.

2. Weiss JP, Blaivas JG, Stember DS, Brooks MM. Nocturia in adults: etiology and classification. Neurourol Urodyn. 1998; 17:467–472. PMID: 9776009.

3. Irwin DE, Milsom I, Hunskaar S, Reilly K, Kopp Z, Herschorn S, et al. Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur Urol. 2006; 50:1306–1314. discussion 1314–5. PMID: 17049716.

4. Muscatello DJ, Rissel C, Szonyi G. Urinary symptoms and incontinence in an urban community: prevalence and associated factors in older men and women. Intern Med J. 2001; 31:151–160. PMID: 11478344.

5. Schatzl G, Temml C, Schmidbauer J, Dolezal B, Haidinger G, Madersbacher S. Cross-sectional study of nocturia in both sexes: analysis of a voluntary health screening project. Urology. 2000; 56:71–75. PMID: 10869627.

6. Stewart RB, Moore MT, May FE, Marks RG, Hale WE. Nocturia: a risk factor for falls in the elderly. J Am Geriatr Soc. 1992; 40:1217–1220. PMID: 1447437.

7. Shao IH, Wu CC, Hsu HS, Chang SC, Wang HH, Chuang HC, et al. The effect of nocturia on sleep quality and daytime function in patients with lower urinary tract symptoms: a crosssectional study. Clin Interv Aging. 2016; 11:879–885. PMID: 27418814.

8. Chapple C, Castro-Diaz D, Chuang YC, Lee KS, Liao L, Liu SP, et al. Prevalence of lower urinary tract symptoms in China, Taiwan, and South Korea: results from a cross-sectional, population-based study. Adv Ther. 2017; 34:1953–1965. PMID: 28687936.

9. Yoshimura K, Terada N, Matsui Y, Terai A, Kinukawa N, Arai Y. Prevalence of and risk factors for nocturia: analysis of a health screening program. Int J Urol. 2004; 11:282–287. PMID: 15147543.

10. Bright E, Drake MJ, Abrams P. Urinary diaries: evidence for the development and validation of diary content, format, and duration. Neurourol Urodyn. 2011; 30:348–352. PMID: 21284023.

11. Lee YS, Lee KS, Jung JH, Han DH, Oh SJ, Seo JT, et al. Prevalence of overactive bladder, urinary incontinence, and lower urinary tract symptoms: results of Korean EPIC study. World J Urol. 2011; 29:185–190. PMID: 19898824.

12. Agarwal A, Eryuzlu LN, Cartwright R, Thorlund K, Tammela TL, Guyatt GH, et al. What is the most bothersome lower urinary tract symptom? Individual- and population-level perspectives for both men and women? Eur Urol. 2014; 65:1211–1217. PMID: 24486308.

13. Zhang L, Zhu L, Xu T, Lang J, Li Z, Gong J, et al. A populationbased survey of the prevalence, potential risk factors, and symptom-specific bother of lower urinary tract symptoms in adult Chinese women. Eur Urol. 2015; 68:97–112. PMID: 25572826.

14. Miranda Ede P, Gomes CM, Torricelli FC, de Bessa J Júnior, de Castro JE, Ferreira BR, et al. Nocturia is the lower urinary tract symptom with greatest impact on quality of life of men from a community setting. Int Neurourol J. 2014; 18:86–90. PMID: 24987561.

15. Dani H, Esdaille A, Weiss JP. Nocturia: aetiology and treatment in adults. Nat Rev Urol. 2016; 13:573–583. PMID: 27455894.

16. Coyne KS, Zhou Z, Bhattacharyya SK, Thompson CL, Dhawan R, Versi E. The prevalence of nocturia and its effect on healthrelated quality of life and sleep in a community sample in the USA. BJU Int. 2003; 92:948–954. PMID: 14632853.

17. Wang Y, Hu H, Xu K, Wang X, Na Y, Kang X. Prevalence, risk factors and the bother of lower urinary tract symptoms in China: a population-based survey. Int Urogynecol J. 2015; 26:911–919. PMID: 25653032.

18. Choo MS, Ku JH, Park CH, Lee YS, Lee KS, Lee JG, et al. Prevalence of nocturia in a Korean population aged 40 to 89 years. Neurourol Urodyn. 2008; 27:60–64. PMID: 17565726.

19. Matthiesen TB, Rittig S, Nørgaard JP, Pedersen EB, Djurhuus JC. Nocturnal polyuria and natriuresis in male patients with nocturia and lower urinary tract symptoms. J Urol. 1996; 156:1292–1299. PMID: 8808857.

20. Eckhardt MD, van Venrooij GE, van Melick HH, Boon TA. Prevalence and bothersomeness of lower urinary tract symptoms in benign prostatic hyperplasia and their impact on well-being. J Urol. 2001; 166:563–568. PMID: 11458069.