J Korean Orthop Assoc.  2019 Jun;54(3):276-280. 10.4055/jkoa.2019.54.3.276.

Unusual Semimembranosus Muscle Metastasis from Hepatocellular Carcinoma

  • 1Department of Orthopedic Surgery, Dong-A University College of Medicine, Busan, Korea. libi33@dau.ac.kr


Hepatocellular carcinoma is one of the most common cancers worldwide. Extrahepatic metastasis commonly occur in the lung, lymph, nodes, bone, and adrenal glands. On the other hand, a metastasis of hepatocellular carcinoma to the skeletal muscle is rare. A 42-year-old woman presented for evaluation of a palpable mass with tenderness in her right thigh area. She has been diagnosed with hepatocellular carcinoma and pulmonary metastasis seven years ago and has received treatment. We performed incisional biopsy with suspicion of hepatocellular carcinoma metastasis from imaging studies and blood test results. The patient was finally diagnosed with metastasis of hepatocellular carcinoma in the semimembranosus muscle and treated by extensive resection. We report this case with a review of the relevant literature.


semimembranosus muscle; hepatocellular carcinoma; metastasis
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