Nucl Med Mol Imaging.  2019 Jun;53(3):231-234. 10.1007/s13139-019-00591-0.

Ipsilateral Hyperhidrosis: Atypical Symptom of Small Lung Adenocarcinoma Evaluated by ¹⁸F-FDG PET-CT

Affiliations
  • 1Department of Nuclear Medicine, Chungbuk National University Hospital, Cheongju, South Korea.
  • 2Department of Internal Medicine, College of Medicine, Chungbuk National University and Chungbuk National University Hospital, Cheongju, South Korea.
  • 3Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungbuk National University and Chungbuk National University Hospital, 410 Sungbong-Ro, Heungduk-Gu, Cheongju, Chungbuk 361-763, South Korea. mwille@naver.com

Abstract

A 45-year-old male visited our clinic due to right palmar anhidrosis and contralateral hyperhidrosis. Chest computed tomography (CT) showed a solitary pulmonary nodule with mediastinal lymph node enlargement, but a cause for atypical palmar anhidrosis was not identified. Subsequent fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed (PET/CT) revealed a localized pleural metastasis at the right apex with direct invasion of the paravertebral sympathetic chain. The pleural metastasis, which was not seen on chest CT, evoked ipsilateral anhidrosis independent of a mass effect or direct invasion by the primary lung tumor. 18F-FDG PET/CT can be helpful in identifying the cause of atypical symptoms in patient with small sized lung cancer.

Keyword

Lung adenocarcinoma; Hyperhidrosis; ¹⁸F-FDG PET/CT; Pleuralmetastasis

MeSH Terms

Adenocarcinoma*
Electrons
Fluorodeoxyglucose F18
Humans
Hyperhidrosis*
Hypohidrosis
Lung Neoplasms
Lung*
Lymph Nodes
Male
Middle Aged
Neoplasm Metastasis
Positron-Emission Tomography and Computed Tomography
Solitary Pulmonary Nodule
Thorax
Tomography, X-Ray Computed
Fluorodeoxyglucose F18
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