Korean J Pancreas Biliary Tract.  2016 Jul;21(3):174-179. 10.15279/kpba.2016.21.3.174.

A Case of Intrahepatic Sarcomatoid Cholangiocarcinoma Mimicking Liver Abscess

Affiliations
  • 1Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea. kwmin.kim@samsung.com

Abstract

Sarcomatoid transformation of intrahepatic cholangiocarcinoma is rarely found but usually has very poor prognosis due to the lack of effective approaches for early detection and its aggressive nature. We report a case of this tumor type, in a 60-year-old man who was referred to our hospital for further evaluation of screening-detected, asymptomatic hepatic lesion. Clinical diagnosis was elusive despite performance of different imaging modalities and a transcutaneous liver biopsy. Pathology of the surgically resected tumor demonstrated intrahepatic sarcomatoid cholangiocarcinoma. In our case, tumor cells expressed strong immunoreactivity to both cytokeratin-19 and vimentin. We assume the relatively good prognosis of this patient would be expected because surgery played a critical role at an early stage of the tumor.

Keyword

Cholangiocarcinoma; Sarcomatoid; Spindle cell; Cytokeratin; Vimentin
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