Ann Surg Treat Res.  2019 Jun;96(6):283-289. 10.4174/astr.2019.96.6.283.

Long-term effect of bariatric surgery versus conventional therapy in obese Korean patients: a multicenter retrospective cohort study

  • 1Department of Surgery, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
  • 2Department of Surgery, Inha University School of Medicine, Incheon, Korea.
  • 3National Evidence-based Healthcare Collaborating Agency, Seoul, Korea.
  • 4Department of Surgery, Soonchunhyang University Seoul Hospital, Seoul, Korea.
  • 5Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
  • 6Department of Surgery, Gachon University College of Medicine, Incheon, Korea.
  • 7Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 8Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 9Department of Surgery, CHA Gangnam Medical Center, CHA University School of Medicine, Seoul, Korea.
  • 10Department of Family Medicine, Ewha Women's University School of Medicine, Seoul, Korea.
  • 11Department of Family Medicine, Inha University School of Medicine, Incheon, Korea.
  • 12College of Pharmacy, Kyungpook National University, Daegu, Korea.


Long-term results following bariatric surgery compared to conventional treatments has never been reported in morbidly obese Korean patients. This study aimed to evaluate the long-term efficacy of bariatric surgery in morbidly obese Korean patients compared to conventional medical treatments.
In this multicenter retrospective cohort study, we reviewed 137 obese subjects between January 2008 and February 2011 with a body mass index (BMI) > 30 kg/m2 who had more than 5 years of follow-up clinical data after bariatric surgery (surgery group, n = 49) or conventional treatment (conventional treatment group, n = 88). Anthropometric data and the status of comorbidities were compared between the 2 groups.
The median follow-up period was 72.1 months (range 19.3-109.7 months). At the last follow-up, the surgery group showed a greater amount of total weight loss than the conventional treatment group (24.9% vs. 2.8%, P < 0.001). The prevalence of diabetes and hypertension significantly decreased in the surgery group, while the conventional treatment group showed a marked increase in these comorbidities. In the surgery group, Roux-en-Y gastric bypass and sleeve gastrectomy achieved comparable long-term weight loss (26.5% vs. 22.4%, respectively; P = 0.087).
In the long-term, bariatric surgery achieved and maintained significantly greater weight reduction, as well as a decrease in obesity-related comorbidities, than did conventional medical therapy in morbidly obese Korean patients.


Morbid obesity; Bariatric surgery; Gastric bypass; Gastrectomy
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