Korean J Dermatol.  2019 Mar;57(3):152-155.

A Case of Peripheral T-cell Lymphoma, Unspecified Presenting as Multiple Ulcerative Tumors

• Cheon DU
• Jang JW
• Han SS
• Seo HM
• Kim JS

Abstract

Peripheral T cell lymphoma, unspecified (PTCL-U) comprises a heterogenous group of mature T-cell lymphomas that do not match with any defined T-cell entities in the current classification system. A 68-year-old man presented with extensive erythematous to brownish ulcerative tumors with yellowish discharge on the neck, trunk, and both upper extremities that had persisted for the past 7 months. Histological findings showed medium- to large-sized pleomorphic lymphocytes with cellular atypia infiltrating the deep dermis and subcutis. Immunohistochemical analysis of specimens from this patient revealed positive staining for CD2, CD45, and granzyme B and mildly positive staining for CD3, CD4, CD30, and CD79a. Based on these clinico-pathological findings, the patient was finally diagnosed with PTCL-U. We report herein a rare case of PTCL-U presenting as multiple ulcerative tumors.

Keyword

Peripheral T-cell lymphoma; Unspecified

MeSH Terms

Aged
Classification
Dermis
Granzymes
Humans
Lymphocytes
Lymphoma, T-Cell
Lymphoma, T-Cell, Peripheral*
Neck
T-Lymphocytes
Ulcer*
Upper Extremity
Granzymes