Ann Geriatr Med Res.  2019 Mar;23(1):38-41. 10.4235/agmr.19.0005.

Newly Diagnosed Sarcopenia and Alzheimer's Disease in an Older Patient With Chronic Inflammation

• Kim SH
• Sin DS
• Lim JY

• KMID: 2446691
• DOI: http://doi.org/10.4235/agmr.19.0005

Abstract

A 78-year-old man presented with the aggravation of weakness in the lower extremities, gait disturbance, and cognitive impairment. He was diagnosed with sarcopenia, distal sensorimotor polyneuropathy, and Alzheimer's disease. Low-grade chronic elevation of inflammatory markers was also revealed. We assumed that chronic low-grade inflammation with aging, also called "inflammaging," contributed to the development of multiple comorbidities. After multidisciplinary treatment and comprehensive rehabilitation, he could ambulate again with minimal to moderate assistance. Various age-related disorders should be suspected when older patients present with chronic low-grade inflammation.

Keyword

Inflammation; Sarcopenia; Alzheimer disease

MeSH Terms

Aged
Aging
Alzheimer Disease*
Cognition Disorders
Comorbidity
Gait
Humans
Inflammation*
Lower Extremity
Polyneuropathies
Rehabilitation
Sarcopenia*