J Korean Soc Radiol.  2019 Mar;80(2):213-225. 10.3348/jksr.2019.80.2.213.

A Review of Three-Dimensional Printing Technology for Medical Applications

• Lee S
• Kim T
• Hong D
• Ock J
• Kwon J
• Gwon E
• Kwon J
• Seo JB
• Chae EJ
• Yang DH
• Kim CS
• Kyung YS
• Ko BS
• Choi S
• Sa HS
• Kim N

• KMID: 2442514
• DOI: http://doi.org/10.3348/jksr.2019.80.2.213

Abstract

Three-dimensional (3D) printing technology, with additive manufacturing, can aid in the production of various kinds of patient-specific medical devices and implants in medical fields, which cannot be covered by mass production systems for producing conventional devices/implants. The simulator-based medical image demonstrates the anatomical structure of the disease, which can be used for education, diagnosis, preparation of treatment plan and preoperative surgical guide, etc. The surgical guide is used as a patient-specific medical device for guiding incision, resection, insertion, and marking. As 3D printers can output materials that can be inserted into the human body, the patient-specific implant device that reflects the patient's anatomy and surgical plan could be of relevance. In addition, patient-specific aids, including gibs, splints, prostheses, and epitheses, could be used for a better outcome. Finally, bio-printing is also used to cultivate cells to produce functional artificial tissues.

MeSH Terms

Diagnosis
Education
Human Body
Models, Anatomic
Patient-Specific Modeling
Precision Medicine
Printing, Three-Dimensional*
Prostheses and Implants
Splints
Technology, Radiologic

Figure

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  Fig. 1. Procedure for the application of 3DP in medicine. CAD = computer-aided design, 3DP = three-dimensional printing

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  Fig. 2. Categories for application of 3D printing in medicine. 3D = three-dimensional

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  Fig. 3. Patient-specific simulators of kidney cancer.

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  Fig. 4. Patient-specific simulators for lung transplantation.

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  Fig. 5. Surgical guide for facial transplant. Adapted from 3D Systems. Available from: URL: https://ko.3dsystems.com/blog/2015/11/virtual-surgical-planning-assists-full-face-transplant(52).

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  Fig. 6. Patient-specific surgical guide for BCS. A. Three segmented breast cancer. B. A designed surgical guide for BCS. C. Three-dimensional-printed surgical guide for BCS. D. The marked outline of breast cancer on the skin. E. Resected breast cancer tissue. BCS = breast-conserving surgery

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  Fig. 7. Pilot study of patient-specific implant device of flexible material. A. CT-based 3D reconstruction of patient-specific dead zone after pneumonectomy. B. 3D-modeled dead zone and frame for molding. C. Fabricated negative mold with silicone material. D. Final product of spacer for dead zone with silicone material using molding technique (6). 3D = three-dimensional Adapted from Kim et al. Korean J Radiol 2016;17:182–197, with permission of The Korean Society of Radiology (6).

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  Fig. 8. Patient-specific splint.

Reference

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