Korean J Dermatol.  2019 Feb;57(2):80-83.

A Case of Cutaneous Metastasis of Nasopharyngeal Carcinoma on the Face

Affiliations
  • 1Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea. stellarnight@naver.com

Abstract

Nasopharyngeal carcinoma is a unique head and neck malignant tumor in terms of epidemiology, pathology, and prognosis. It has been demonstrated that the pathogenesis of nasopharyngeal carcinoma is associated with Epstein-Barr virus (EBV). A 52-year-old man was referred for a solitary erythematous patch on the left cheek. The biopsy specimen showed nasopharyngeal carcinoma with positive EBV RNA stain. The incidence of cutaneous metastasis is rare. When skin metastasis develops, it suggests a progressive state of the disease, although it is common for distant metastasis to occur at other sites. Herein, we describe our experience with an uncommon case of nasopharyngeal carcinoma presenting cutaneous metastasis.

Keyword

Cutaneous metastasis; Nasopharyngeal carcinoma

MeSH Terms

Biopsy
Cheek
Epidemiology
Head
Herpesvirus 4, Human
Humans
Incidence
Middle Aged
Neck
Neoplasm Metastasis*
Pathology
Prognosis
RNA
Skin
RNA
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