Korean J Pediatr Infect Dis.  1999 Nov;6(2):261-266. 10.14776/kjpid.1999.6.2.261.

A Case of Vancomycin-Resistant Enterococcal Sepsis in Neonate

• Bae SJ
• Choi GJ
• Kim CS
• Lee SL
• Kim HS
• Kang CM

• KMID: 2440265
• DOI: http://doi.org/10.14776/kjpid.1999.6.2.261

Abstract

Vancomycin-resistant enterococcus(VRE) was first isolated from various specimens of patients with renal failure or leukemia in 1988. Thereafter VRE has been increasing gradually and became one of the clinically important pathogenic organisms currently. We experienced a case of E. faecalis sepsis in a 4 day old neonate. She was born at 39 weeks gestational age with 2,900gm weight by Cesarean section delivery due to breech presentation. She had swelling and motion limitation of the left knee joint with fever for one day at age of 4 day and was transfered to our hospital. Ultrasonographic examination of her left knee joint showed some inflammatory change. E. faecalis was isolated from the blood. The organism showed resistance to vancomycin on drug susceptibility test using BHI agar screening test and disk diffusion method. After treatment with ampicillin-sulbactam for 3 weeks the baby was improved. Although VRE infection has been considered rare in Korea, considerable number of demonstrative studies about VRE isolation have been reported recently thus adequate countermeasures are needed to reduce the emergence and prevent nosocomial spreading of this organism.

Keyword

Vancomycin-resistant enterococcus; Sepsis; Neonate

MeSH Terms

Agar
Breech Presentation
Cesarean Section
Diffusion
Female
Fever
Gestational Age
Humans
Infant, Newborn*
Knee Joint
Korea
Leukemia
Mass Screening
Methods
Pregnancy
Renal Insufficiency
Sepsis*
Vancomycin
Agar
Vancomycin