Korean J Pediatr Infect Dis.  2001 Nov;8(2):241-246. 10.14776/kjpid.2001.8.2.241.

Two Case of Burkholderia cepacia Sepsis

• Park SS
• Ahn SR
• Park SE
• Lim YT
• Chang CH

• KMID: 2440192
• DOI: http://doi.org/10.14776/kjpid.2001.8.2.241

Abstract

Burkholderia cepacia, a widespread gram-negative environmental bacillus associated with nosocomial infection, is considered to be of relatively low virulence and rarely to cause invasive disease in immunocompromised patients. Nosocomial infections resulting from the use of contaminted medication, antiseptics and instruments have also been reported in otherwise healthy hosts. We experienced two cases of B. cepacia sepsis in 10 year-old male who was medicated with the anticancer drugs for the treatment of acute lymphoblastic leukemia(ALL) and in 15 day-old newborn who was examined with voiding vesicourethrography(VCUG) for the evaluation of congenital hydronephrosis. The organism isolated from serial blood culture in ALL patient and from serial blood culture and urine culture in newborn examined with VCUG. The former ALL patient improved after antibacterial medication of imipenem and the latter newborn improved after treatment with imipenem and trimethoprim-sulfamethoxazole.

Keyword

Burkholderia cepacia; Sepsis

MeSH Terms

Anti-Infective Agents, Local
Bacillus
Burkholderia cepacia*
Burkholderia*
Cross Infection
Humans
Hydronephrosis
Imipenem
Immunocompromised Host
Infant, Newborn
Male
Sepsis*
Trimethoprim, Sulfamethoxazole Drug Combination
Virulence
Anti-Infective Agents, Local
Imipenem
Trimethoprim, Sulfamethoxazole Drug Combination