Ann Hepatobiliary Pancreat Surg.  2019 Feb;23(1):74-76. 10.14701/ahbps.2019.23.1.74.

Follicular dendritic cell sarcoma: Rare presentation of incidental large hepatic mass

• Ang WW
• Bundele MM
• Shelat VG

• KMID: 2439050
• DOI: http://doi.org/10.14701/ahbps.2019.23.1.74

Abstract

Follicular dendritic cell sarcoma (FDCS) is a rare tumor, and it is even rarer for FDCS, to affect liver. FDCS is recognized as a distinct entity by the World Health Organization (WHO). Diagnosis is usually post resection and based on typical immunohistochemical stains. Resection with histologic negative margins is proposed, as a mainstay of therapy. We report a 63-year-old woman with large FDCS of the liver, managed with right hemihepatectomy. She remains disease-free at 48 months.

Keyword

Hepatectomy; Sarcoma

MeSH Terms

Coloring Agents
Dendritic Cell Sarcoma, Follicular*
Dendritic Cells, Follicular*
Diagnosis
Female
Hepatectomy
Humans
Liver
Middle Aged
Sarcoma
World Health Organization
Coloring Agents

Figure

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  Fig. 1 Computed tomography scan of the hepatic mass: Axial (A) and coronal sections (B).

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  Fig. 2 Gross photograph showing the cut surface of resected tumour showing circumscribed fleshy tumor with focal necrosis.

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  Fig. 3 Microscopic findings. (A) Spindle cells in storiform pattern and whorls with dense interspersed lymphoplasmacytic infiltrate (H&E ×400). (B) Diffuse and strong positive immunohistochemical staining for CD21. (C) Large areas of positive immunohistochemical staining for CD23. (D) Positive immunohistochemical staining for Epstein-Barr virus-encoded RNA.

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