Ann Hepatobiliary Pancreat Surg.  2019 Feb;23(1):56-60. 10.14701/ahbps.2019.23.1.56.

Effect of early and delay starting of enteral feeding in post-pancreaticoduodenectomy patients

• Das BC
• Haque M
• Uddin MS
• Nur-E-Elahi M
• Khan ZR

• KMID: 2439046
• DOI: http://doi.org/10.14701/ahbps.2019.23.1.56

Abstract

BACKGROUNDS/AIMS
This study was undertaken to see the effect of early starting of enteral feeding after pancreatoduodenectomy (PD). The results were compared with existing nutritional practice in which enteral feeding started, usually after 7 to 8 postoperative day (PODs) in our institute.
METHODS
Thirty patients whome underwent a PD from January 2016 to December 2016 were included in the study. They were divided into two groups, I and II. In group I (n=15), enteral feeding was started from the 2(nd) POD through the nasojejunal feeding tube along with parenteral partial nutrition support. In group II (n=15), no enteral feeding was given up to seventh and eighth PODs, except the perenteral feeding. Post-operatively, serum albumin levels, total lymphocyte count, total bilirubin levels, serum alkaline phosphate levels were measured for two weeks postoperatively in all the patients for assessing nutritional, immunological and cholestasis status. The mortality, morbidity and lengths of post-operative hospital stay were also recorded.
RESULTS
Postoperatively, the serum albumin level and lymphocyte count decreased from the pre-operative level on the third POD and it gradually increased from the seventh POD onwards in both groups. However, they remained persistently higher in group I than group II. The total bilirubin and alkaline phosphatase decreased to normal levels within the seventh POD in Group I. However, they remained higher than normal levels on POD 14 in Group II. The morbidity and hospital stay was significantly lower in group I than group II.
CONCLUSIONS
Early enteral feeding should be considered after PD. This is because it will improve nutritional, immunological status and cholestasis. Therefore, it reduces morbidity and shortens the hospital stay.

Keyword

Early and delay; Enteral feeding; Pancreatoduodenectomy

MeSH Terms

Alkaline Phosphatase
Bilirubin
Cholestasis
Enteral Nutrition*
Humans
Length of Stay
Lymphocyte Count
Mortality
Pancreaticoduodenectomy
Serum Albumin
Alkaline Phosphatase
Bilirubin
Serum Albumin

Figure

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  Fig. 1 Changes in serum albumin level between two groups.

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  Fig. 2 Changes in blood lymphocyte count between two groups.

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  Fig. 3 (A) Changes in serum total bilirubin level between two groups. (B) Changes in serum alkaline phosphate level between two groups.

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