J Breast Cancer.  2017 Sep;20(3):217-227. 10.4048/jbc.2017.20.3.217.

Sentinel Lymph Node Biopsy in Breast Cancer: A Clinical Review and Update

• Zahoor S
• Haji A
• Battoo A
• Qurieshi M
• Mir W
• Shah M

• KMID: 2438987
• DOI: http://doi.org/10.4048/jbc.2017.20.3.217

Abstract

Sentinel lymph node biopsy has become a standard staging tool in the surgical management of breast cancer. The positive impact of sentinel lymph node biopsy on postoperative negative outcomes in breast cancer patients, without compromising the oncological outcomes, is its major advantage. It has evolved over the last few decades and has proven its utility beyond early breast cancer. Its applicability and efficacy in patients with clinically positive axilla who have had a complete clinical response after neoadjuvant chemotherapy is being aggressively evaluated at present. This article discusses how sentinel lymph node biopsy has evolved and is becoming a useful tool in new clinical scenarios of breast cancer management.

Keyword

Breast neoplasms; Lymphatic metastasis; Neoadjuvant therapy; Sentinel lymph node biopsy

MeSH Terms

Axilla
Breast Neoplasms*
Breast*
Drug Therapy
Humans
Lymphatic Metastasis
Neoadjuvant Therapy
Sentinel Lymph Node Biopsy*