Clin Endosc.  2019 Jan;52(1):72-75. 10.5946/ce.2018.058.

A Case of Esophageal Squamous Cell Carcinoma in situ Arising from Esophageal Squamous Papilloma

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. adagio@catholic.ac.kr
  • 2Department of Hospital Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.

Abstract

Squamous papilloma is a common benign tumor of the esophagus. Patients with papilloma are usually asymptomatic, and they are diagnosed incidentally during esophagogastroduodenoscopy. Most papillomas are small and easily removed by forceps biopsy. Recurrence of papilloma after removal is rare. Human papilloma virus infection is supposed to play a role in the development of esophageal papilloma; however, malignant transformation of papilloma is extremely unusual. Here, we report a case of malignant transformation of esophageal squamous papilloma at the gastroesophageal junction into squamous cell carcinoma in situ, which was treated by endoscopic submucosal dissection.

Keyword

Papilloma; Carcinoma, squamous cell; Carcinoma in situ; Endoscopy, digestive system

MeSH Terms

Biopsy
Carcinoma in Situ
Carcinoma, Squamous Cell*
Endoscopy, Digestive System
Epithelial Cells*
Esophagogastric Junction
Esophagus
Humans
Papilloma*
Papillomaviridae
Recurrence
Surgical Instruments
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