Korean J Dermatol.  2018 Dec;56(10):624-627.

Periocular Allergic Contact Dermatitis Associated with the Use of Ofloxacin Ophthalmic Ointment: A Case Report

• Jo JW
• Jeong HB
• Shin YB
• Kang KR
• Kim CY

Abstract

Allergic contact dermatitis is an inflammatory condition associated with periorbital erythema, edema, and pruritus. The periorbital skin is relatively thin compared with the skin over other facial areas; therefore, it is vulnerable to allergen penetration and may show a variety of cutaneous manifestations. Recently, vision enhancement surgery is a widely performed procedure, and the prevalence of senile cataract and glaucoma is increasing. The prevalence of periocular allergic contact dermatitis is increasing secondary to the growing use of topical ophthalmic medications. Several studies in Korea have reported periocular allergic contact dermatitis secondary to the use of topical ophthalmic medications including latanoprost (Latano®), fluorometholone (Tolon®), polymyxin B (Terramycin®), atropine sulfate (Atropine®), neomycin sulfate (Cambison®), and befunolol hydrochloride (Bentos®), among others. However, ofloxacin (Effexin®)-induced allergic contact dermatitis has not been reported in the domestic and/or foreign literature. We report a case of periocular allergic contact dermatitis secondary to the use of ofloxacin ophthalmic ointment.

Keyword

Allergic contact dermatitis; Ofloxacin; Ophthalmic ointment

MeSH Terms

Atropine
Cataract
Dermatitis, Allergic Contact*
Edema
Erythema
Fluorometholone
Glaucoma
Korea
Neomycin
Ofloxacin*
Polymyxin B
Prevalence
Pruritus
Skin
Atropine
Fluorometholone
Neomycin
Ofloxacin
Polymyxin B