Korean J Dermatol.  2018 Jun;56(5):338-342.

Progressive Cribriform and Zosteriform Hyperpigmentation: A Case Series and Review of the Literature

• Lee SK
• Suh JH
• Kim MS
• Lee UH

Abstract

Progressive cribriform and zosteriform hyperpigmentation (PCZH) is a distinctive pigmentary disorder observed along the lines of Blaschko. Clinically, the lesions appear as uniformly tan, cribriform macular hyperpigmentation with a zosteriform distribution, without a history of rash, injury, inflammation, or other associated cutaneous or internal abnormalities. Histopathological specimens show increased melanin pigmentation in the basal cell layer with a complete absence of nevus cells. We report 8 cases of PCZH and review the literature on this peculiar disorder.

Keyword

Progressive cribriform and zosteriform hyperpigmentation; Lines of Blaschko

MeSH Terms

Exanthema
Hyperpigmentation*
Inflammation
Melanins
Nevus
Pigmentation
Triacetoneamine-N-Oxyl
Melanins
Triacetoneamine-N-Oxyl