Korean J Otorhinolaryngol-Head Neck Surg.  2018 May;61(5):258-262. 10.3342/kjorl-hns.2016.17426.

A Case of Sebaceous Carcinoma of the Submandibular Gland

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon, Korea. hs-piao@hanmail.net
  • 2Nano-Bio Regenerative Medical Institute, College of Medicine, Hallym University, Chuncheon, Korea.

Abstract

Sebaceous carcinoma of the salivary gland is an extremely unordinary malignancy occurring mainly in the parotid gland. Sebaceous carcinoma arising in the submandibular gland is exceptional and only three cases have been reported in the literature. We herein present a unique case of sebaceous carcinoma of the submandibular gland, the first to be reported in literature in South Korea. An 85-year-old man visited our hospital complaining of a progressively enlarging submandibular mass with tenderness and ipsilateral facial palsy. We performed a wide excision of the mass with superficial parotidectomy and modified neck dissection. Microscopic and immunohistochemical examinations demonstrated sebaceous carcinoma of low grade differentiation. Further adjuvant radiotherapy was rejected and the patient was followed up for five months. The optimal treatment of sebaceous carcinoma of the salivary gland is still not established due to the rarity of the disease. When more cases are reported, the clinicopathologic characteristics will be better understood.

Keyword

Salivary gland neoplasms; Sebaceous carcinoma; Submandibular gland neoplasms

MeSH Terms

Aged, 80 and over
Facial Paralysis
Humans
Korea
Neck Dissection
Parotid Gland
Radiotherapy, Adjuvant
Salivary Gland Neoplasms
Salivary Glands
Submandibular Gland Neoplasms
Submandibular Gland*
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