J Korean Neurol Assoc.
2018 May;36(2):86-88. 10.17340/jkna.2018.2.4.
Hyponatremia-induced Seizures in Schizophrenic Patient Treated with Olanzapine
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- 1Department of Neurology, Yeungnam University College of Medicine, Daegu, Korea. sejinmayo@ynu.ac.kr
- KMID: 2436103
- DOI: http://doi.org/10.17340/jkna.2018.2.4
Abstract
- Severe hyponatremia (serum sodium concentration <120 mEq/L) is a well-known etiology of acute symptomatic seizure. Severe hyponatremia may occur as a rare but clinically important adverse reaction of psychotrophic drugs. Among them, patients with psychogenic polydipsia have especially higher risk of severe hyponatremia. We present a schizophrenic patient with polydipsia who developed severe hyponatremia and symptomatic seizures while receiving olanzapine treatment.
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