Korean J Med.  2018 Apr;93(2):220-223. 10.3904/kjm.2018.93.2.220.

Acute Thrombotic Thrombocytopenic Purpura with Right Heart Failure Following Total Knee Replacement Surgery

Affiliations
  • 1Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
  • 2Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sbhong@amc.seoul.kr

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening condition characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal insufficiency, neurological abnormalities, and fever. Cardiac involvement is not uncommon and can be fatal; however, right ventricular heart involvement after surgery is rare. Here, we report a case of TTP presenting with right ventricular heart failure after total knee replacement surgery. TTP was successfully treated with four rounds of plasma exchange. The patient made a full recovery and was discharged after 11 weeks.

Keyword

Purpura, Thrombotic thrombocytopenic; Orthopedics; Heart failure

MeSH Terms

Anemia, Hemolytic
Arthroplasty, Replacement, Knee*
Fever
Heart Failure*
Heart*
Humans
Orthopedics
Plasma Exchange
Purpura, Thrombotic Thrombocytopenic*
Renal Insufficiency
Thrombocytopenia
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