Ann Dermatol.  2012 May;24(2):200-202.

Paroxysmal Supraventricular Tachycardia in an Infant with Hand, Foot, and Mouth Disease

• Hu P
• Hou S
• Du PF
• Li JB
• Ye Y

Abstract

An 11-month-old male infant was admitted to our hospital with fever, fussiness, poor feeding, vomiting, and tachypnea for two days prior. Physical examination revealed sporadic papules and vesicles occurring on his hands, feet, face, and perianal mucosa. Enterovirus 71 was identified from both throat swab and vesicle fluid using virus isolation techniques. The patient's heart rate fluctuated in a very narrow range from 180~210/beats/min regardless of his physiologic state. An electrocardiogram showed P-waves buried within or occurring just after regular, narrow, QRS complexes. The patient was diagnosed as having hand, foot, and mouth disease in combination with paroxysmal supraventricular tachycardia (PSVT). The child recovered well with symptomatic treatment, including intravenous administration of acyclovir, glucocorticoids, immunoglobulin, adenosine, and sotalol. PSVT was terminated within 36 hours of hospitalization. The skin lesions became crusted on the third day, and then proceeded to heal spontaneously. Here we report on this unusual case and review the associated literature.

Keyword

Electrocardiography; Hand; foot and mouth disease; Enterovirus 71; Paroxysmal supraventricular tachycardia

MeSH Terms

Acyclovir
Adenosine
Administration, Intravenous
Animals
Child
Electrocardiography
Enterovirus
Fever
Foot
Foot-and-Mouth Disease
Glucocorticoids
Hand
Heart Rate
Hospitalization
Humans
Immunoglobulins
Infant
Male
Mouth
Mouth Diseases
Mucous Membrane
Pharynx
Physical Examination
Skin
Sotalol
Tachycardia, Supraventricular
Tachypnea
Viruses
Vomiting
Acyclovir
Adenosine
Glucocorticoids
Immunoglobulins
Sotalol

Figure

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  Fig. 1 Sporadic papules and vesicles occurred on face, hands, and feet of an 11-month-old male infant from Hefei City, Anhui province, with enterovirus 71 infection (blue arrow).

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  Fig. 2 A 6-lead surface electrocardiogram showing P-waves buried within or occurring just after regular, narrow QRS complexes.

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