Ann Dermatol.  2016 Feb;28(1):136-137. 10.5021/ad.2016.28.1.136.

Eruptive Xanthoma with Acute Pancreatitis in a Patient with Hypertriglyceridemia and Diabetes

• Inoue-Nishimoto T
• Hanafusa T
• Hirohata A
• Kiyohara-Mabuchi E
• Mizoguchi
• Matsumoto
• Sakamoto S
• Zenibayashi M
• Miyata S
• Ikegami R

• KMID: 2429503
• DOI: http://doi.org/10.5021/ad.2016.28.1.136

Abstract

No abstract available.

MeSH Terms

Humans
Hypertriglyceridemia*
Pancreatitis*
Xanthomatosis*

Figure

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  Fig. 1 (A) Clinical appearance and (B) dermoscopic appearance of multiple yellowish erythematous papules on the patient's back in October 2013.

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  Fig. 2 Skin biopsy from the erythematous papules present on the patient's waist. (A) At lower magnification, numerous pale areas containing foamy cells infiltrate the dermis, especially the upper dermis and perivascular areas (H&E, ×40). (B) At higher magnification, foamy cells with extracellular lipids are present (×200).

Reference

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2. Parker F. Xanthomas and hyperlipidemias. J Am Acad Dermatol. 1985; 13:1–30.

3. Ladizinski B, Lee KC. Eruptive xanthomas in a patient with severe hypertriglyceridemia and type 2 diabetes. CMAJ. 2013; 185:1600.

4. Parker F, Bagdade JD, Odland GF, Bierman EL. Evidence for the chylomicron origin of lipids accumulating in diabetic eruptive xanthomas: a correlative lipid biochemical, histochemical, and electron microscopic study. J Clin Invest. 1970; 49:2172–2187.

5. Makdsi F, Fall A. Acute pancreatitis with eruptive xanthomas. J Hosp Med. 2010; 5:115.