Korean J Helicobacter Up Gastrointest Res.  2018 Mar;18(1):56-60. 10.7704/kjhugr.2018.18.1.56.

Association between Oral Health and Gastric Neoplastic Lesions

• Cha JH
• Lee DW
• Kim S
• Kim JH
• Moon IS
• Jung DH
• Park JJ
• Youn YH
• Park H

• KMID: 2428900
• DOI: http://doi.org/10.7704/kjhugr.2018.18.1.56

Abstract

BACKGROUND/AIMS
Although several studies have suggested that tooth loss is associated with the risk of gastric cancer, the association between oral health and gastric cancer remains a controversial issue. Thus, we investigated whether oral health is associated with the risk of gastric neoplastic lesions.
MATERIALS AND METHODS
We retrospectively evaluated 391 patients who underwent upper gastrointestinal endoscopic examination between March 2010 and February 2013. The tooth number and the age-related periodontal bone loss score (ArB score) were investigated as parameters of oral health. Gastric neoplastic lesions included adenomas and cancer detected on biopsy examination.
RESULTS
We identified 10 patients (2.6%) with neoplastic lesions. Older age, a higher body mass index, and the presence of Helicobacter pylori infection were significantly associated with neoplastic lesions. However, there was no significant correlation about Kimura-Takemoto classification, ArB score, and tooth number. Multivariate analyses showed that age was significantly associated with neoplastic lesions.
CONCLUSIONS
Our findings demonstrate that oral health (assessed using parameters such as tooth number and ArB score) may not be significantly associated with gastric neoplastic lesions.

Keyword

Bone loss; Helicobacter pylori; Oral health; Stomach neoplasms

MeSH Terms

Adenoma
Alveolar Bone Loss
Biopsy
Body Mass Index
Classification
Helicobacter pylori
Humans
Multivariate Analysis
Oral Health*
Retrospective Studies
Stomach Neoplasms
Tooth
Tooth Loss