Korean J Ophthalmol.  2018 Dec;32(6):517-518. 10.3341/kjo.2018.0057.

Eyelid Swelling and Subconjunctival Infiltration as Ophthalmic Manifestations in a Child with Idiopathic Hypereosinophilic Syndrome

Affiliations
  • 1Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea. resourceful@hanmail.net
  • 2Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
  • 3Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
  • 4Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Child*
Eyelids*
Humans
Hypereosinophilic Syndrome*

Figure

  • Fig. 1 Ocular events and clinical course in a young girl with idiopathic hypereosinophilic syndrome. (A) A 7-year-old girl presenting with a yellowish subconjunctival infiltrative lesion in her left eye. (B) Two weeks after discontinuation of steroid treatment, newly developed left eyelid swelling, caused by a semi-hard mass, was observed. Informed consent has been obtained from patient for treatment and publication. (C,D). Histopathological examination of the tissue obtained from the mass, which was located at the level of the preaponeurotic fat pad, shows dense eosinophilic infiltration (the square magnified on the right shows infiltrating eosinophils in the mass). (C) H&E, ×20. (D) H&E, ×50. (E) Relationships among eosinophil count, ocular events, and immunosuppressive therapy. Ocular events (eyelid swelling and subconjunctival infiltration) occurred when the absolute eosinophil count was >2.0 × 103 cells/µL (red dots) and resolved when the eosinophilia improved (blue dots). This finding suggests that the ocular events were associated with eosinophilia and may provide an index of eosinophilia in patients with hypereosinophilic syndrome.


Reference

1. Hsieh FH. Hypereosinophilic syndrome. Ann Allergy Asthma Immunol. 2014; 112:484–488.
Article
2. Chaine G, Davies J, Kohner EM, et al. Ophthalmologic abnormalities in the hypereosinophilic syndrome. Ophthalmology. 1982; 89:1348–1356.
Article
3. Ramzan M, Chopra Y, Grover AK, Yadav SP. Isolated bilateral uveitis in child with hypereosinophilic syndrome. J Pediatr Hematol Oncol. 2014; 36:e465–e467.
Article
4. Farcet JP, Binaghi M, Kuentz M, et al. A hypereosinophilic syndrome with retinal arteritis and tuberculosis. Arch Intern Med. 1982; 142:625–627.
Article
5. Fauci AS, Harley JB, Roberts WC, et al. NIH conference. The idiopathic hypereosinophilic syndrome. Clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med. 1982; 97:78–92.
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