Clin Endosc.  2018 Sep;51(5):500-501. 10.5946/ce.2018.061.

Ocular Melanoma Recurrence Presenting as Cholestatic Jaundice due to Periampullary Area Metastases

Affiliations
  • 1Section of Gastroenterology, Second Department of Internal Medicine Ippokration Hospital, Thessaloniki, Greece. anassot@yahoo.gr

Abstract

No abstract available.


MeSH Terms

Jaundice, Obstructive*
Melanoma*
Neoplasm Metastasis*
Recurrence*

Figure

  • Fig. 1. Duodenoscopy image showing a periampullary area with blackish hue, a plastic stent inserted in the common bile duct, and a black volcano-like lesion near the major papilla.

  • Fig. 2. (A) Stranded proliferation of spindle-shaped cells with cytoplasmic brightness and nuclear atypia (hematoxylin-eosin, original magnification ×200). (B) Immunohistochemical staining showing positivity for melan-A.


Reference

1. Schuchter LM, Green R, Fraker D. Primary and metastatic diseases in malignant melanoma of the gastrointestinal tract. Curr Opin Oncol. 2000; 12:181–185.
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2. Blecker D, Abraham S, Furth EE, Kochman ML. Melanoma in the gastrointestinal tract. Am J Gastroenterol. 1999; 94:3427–3433.
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3. Marks JA, Rao AS, Loren D, Witkiewicz A, Mastrangelo MJ, Berger AC. Malignant melanoma presenting as obstructive jaundice secondary to metastasis to the ampulla of Vater. JOP. 2010; 11:173–175.
4. Kadakia SC, Parker A, Canales L. Metastatic tumors to the upper gastrointestinal tract: endoscopic experience. Am J Gastroenterol. 1992; 87:1418–1423.
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