Korean J Leg Med.  2018 Nov;42(4):146-152. 10.7580/kjlm.2018.42.4.146.

Increased Ventrolateral Prefrontal Cortex Activation during Accurate Eyewitness Memory Retrieval: An Exploratory Functional Near-Infrared Spectroscopy Study

Affiliations
  • 1Psychological Forensics Division, National Forensic Service, Wonju, Korea. ksham@korea.kr
  • 2Institute of Forensic Medicine and Department of Forensic Medicine, Seoul National University College of Medicine, Seoul, Korea. yoosh@snu.ac.kr

Abstract

We investigated the neural correlates of accurate eyewitness memory retrieval using functional near-infrared spectroscopy. We analyzed oxygenated hemoglobin (HbOâ‚‚) concentration in the prefrontal cortex during eyewitness memory retrieval task and examined regional HbOâ‚‚ differences between observed objects (target) and unobserved objects (lure). We found that target objects elicited increased activation in the bilateral ventrolateral prefrontal cortex, which is known for monitoring retrieval processing via bottom-up attentional processing. Our results suggest bottom-up attentional mechanisms could be different during accurate eyewitness memory retrieval. These findings indicate that investigating retrieval mechanisms using functional nearinfrared spectroscopy might be useful for establishing an accurate eyewitness recognition model.

Keyword

Memory; Recognition; Spectroscopy; near-infrared; Prefrontal cortex; Cognitive neuroscience

MeSH Terms

Cognitive Neuroscience
Memory*
Oxygen
Prefrontal Cortex*
Spectroscopy, Near-Infrared*
Spectrum Analysis
Oxygen

Figure

  • Fig. 1 Schematic of the experimental design. Participants watched mock-crime video and performed recognition task about 1 hour later. Three-word stimulus was presents as a memory cue for which a response was selected from two alternatives (seen or unseen). Participants could witness the stimulus in target condition appeared in mock-crime video, but couldn't witness the stimulus in other conditions (color-changed lure and form-changed lure).

  • Fig. 2 Schematic of functional near-infrared spectroscopy probes and optode locations registered to the Montreal Neurological Institute brain template across prefrontal cortex.

  • Fig. 3 Bilateral ventrolateral prefrontal cortex (VLPFC) showing significant activation differences between the hit and correct rejection conditions. Significantly activated voxels in the hit condition (A) and correct rejection condition (B). (C) Compared to the correct rejection condition, voxels in bilateral VLPFC showed higher activation in the hit condition (uncorrected P<0.005).


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