J Korean Med Sci.
2018 Nov;33(47):e296. 10.3346/jkms.2018.33.e296.
Pregnancy Rates and Outcomes of HIV-Infected Women in Korea
- Affiliations
-
- 1Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea. SERAN@yuhs.ac
- 2Department of Infectious Diseases, Ajou University School of Medicine, Suwon, Korea.
- 3Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
- 4Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
- KMID: 2426355
- DOI: http://doi.org/10.3346/jkms.2018.33.e296
Abstract
- BACKGROUND
Antepartum, intrapartum, and postpartum preventive measures with antiretroviral drugs, appropriate delivery methods, and discouraging breastfeeding significantly decrease the risk of mother-to-child transmission of human immunodeficiency virus (HIV) infection. Herein, we investigated the pregnancy outcomes in HIV-infected Korean women.
METHODS
We retrospectively reviewed medical records of childbearing-age HIV-infected women between January 2005 and June 2017 at four tertiary care hospitals in Korea.
RESULTS
Among a total of 95 HIV infected women of child-bearing age with 587.61 years of follow-up duration, 15 HIV-infected women experienced 21 pregnancies and delivered 16 infants. The pregnancy rate was 3.57 per 100 patient-years. Among the 21 pregnancies, five ended with an induced abortion, and 16 with childbirth including two preterm deliveries at 24 and 35 weeks of gestation, respectively. The two preterm infants had low birth weight and one of them died 10 days after delivery due to respiratory failure. Among the 14 full-term infants, one infant was small for gestational age. There were no HIV-infected infants.
CONCLUSION
The pregnancy rate of HIV-infected women in Korea is lower than that of the general population. Although several adverse pregnancy outcomes were observed, mother-to-child transmission of HIV infection was successfully prevented with effective preventive measures.
MeSH Terms
-
Abortion, Induced
Breast Feeding
Female
Follow-Up Studies
Gestational Age
HIV
HIV Infections
Humans
Infant
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Korea*
Medical Records
Parturition
Postpartum Period
Pregnancy Outcome
Pregnancy Rate*
Pregnancy*
Respiratory Insufficiency
Retrospective Studies
Tertiary Healthcare
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