Diabetes Metab J.  2018 Oct;42(5):433-441. 10.4093/dmj.2018.0010.

Comparison of Competitive Models of Metabolic Syndrome Using Structural Equation Modeling: A Confirmatory Factor Analysis

• Hajian-Tilaki K

• KMID: 2422788
• DOI: http://doi.org/10.4093/dmj.2018.0010

Abstract

BACKGROUND
The purpose of this study was to apply the structural equation modeling (SEM) to compare the fitness of different competing models (one, two, and three factors) of the metabolic syndrome (MetS) in Iranian adult population.
METHODS
Data are given on the cardiometabolic risk factors of 841 individuals with nondiabetic adults from a cross-sectional population-based study of glucose, lipids, and MetS in the north of Iran. The three conceptual hypothesized models (single factor, two correlated factors, and three correlated latent factors) were evaluated by using confirmatory factor analysis with the SEM approach. The summary statistics of correlation coefficients and the model summary fitting indexes were calculated.
RESULTS
The findings show that a single-factor model and a two-correlated factor model had a poorer summary fitting index compared with a three-correlated factor model. All fitting criteria met the conceptual hypothesized three-correlated factor model for both sexes. However, the correlation structure between the three underlying constructs designating the MetS was higher in women than in men.
CONCLUSION
These results indicate the plausibility of the pathophysiology and etiology of MetS being multifactorial, rather than a single factor, in a nondiabetic Iranian adult population.

Keyword

Factor analysis, statistical; Glucose; Lipids; Metabolic syndrome; Obesity; Obesity, abdominal

MeSH Terms

Adult
Factor Analysis, Statistical*
Female
Glucose
Humans
Iran
Male
Obesity
Obesity, Abdominal
Risk Factors
Glucose

Figure

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  Fig. 1 The standardized coefficients between components of metabolic syndrome (MetS) in a single-factor model for males (A) and females (B) (model 1A). WC, waist circumference; MAP, mean arterial pressure; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; FBS, fasting blood glucose.

• 

  Fig. 2 The standardized coefficients between components of metabolic syndrome (MetS) in a single-factor model for males (A) and females (B) (model 1B). WC, waist circumference; BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; FBG, fasting blood glucose.

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  Fig. 3 The standardized coefficients between components of metabolic syndrome in two-factor model for males (A) and females (B). SBP, systolic blood pressure; DBP, diastolic blood pressure; HTN, hypertension; BMI, body mass index; WC, waist circumference; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; FBG, fasting blood glucose.

• 

  Fig. 4 The standardized coefficients between components of metabolic syndrome in three-factor model for males (A) and females (B). BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; HTN, hypertension; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; FBG, fasting blood glucose.

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