J Cerebrovasc Endovasc Neurosurg.  2018 Jun;20(2):106-111. 10.7461/jcen.2018.20.2.106.

Recurrence of Small Cerebral Aneurysms (< 4 mm) Treated Endovascularly Using Target® Nano™ Coils

• Kim SM
• Lee HG
• Choi BS
• Kim JS
• Lee SJ
• Kim HY
• Kim ST
• Jeong YG
• Baek JW
• Jeong HW
• Jin SC

• KMID: 2422604
• DOI: http://doi.org/10.7461/jcen.2018.20.2.106

Abstract

OBJECTIVE
In our series, endovascular coiling with Target® Nanoâ„¢ coils (Stryker Neurovascular, Fremont, CA, USA) with diameters of 1 or 1.5 mm exhibited favorable technical feasibility in the treatment of small cerebral aneurysms (< 4 mm). However, little is known about the recurrence of small cerebral aneurysms treated using Target® Nanoâ„¢ coils. We investigated recurrence following the treatment of small cerebral aneurysms using Target® Nanoâ„¢ coils.
MATERIALS AND METHODS
Between January 2012 and November 2013, 143 patients with 148 small cerebral aneurysms (< 4 mm) were included our study. A total of 135 cerebral aneurysms (91.2%) were unruptured; 45 cerebral aneurysms (30.4%) were treated by endovascular coiling using Target® Nanoâ„¢ coils. Follow-up radiological images were obtained for 132 cerebral aneurysms (89.2%) over a range of 3 to 58 months (mean, 34.3 months; standard deviation, 14.2).
RESULTS
In the group treated with Target® Nanoâ„¢ coils, radiological outcomes revealed complete occlusion in 33 (73.3%), residual necks in eight (17.8%), and residual sacs in four (8.9%) cases. Follow-up radiological outcomes revealed complete occlusion in 35 (77.8%) and residual necks in four (8.9%) cases that exhibited stable coil masses. In the group that was not treated with Target® Nanoâ„¢ coils, radiological outcomes revealed complete occlusion in 69 (67%), residual necks in 18 (17.5%), and residual sacs in 16 (15.5%) cases. Follow-up radiological outcomes revealed complete occlusion in 87 (84.5%) and residual necks (5.8%) in six cases that exhibited stable coil masses. No significant differences were observed in the radiological outcomes or follow-up radiological outcomes between the two groups. No recurrences or retreatments occurred in our series.
CONCLUSION
Endovascular treatment using Target® Nanoâ„¢ coils may be a robust treatment option for small cerebral aneurysms (< 4 mm).

Keyword

Rcurrence of small cerebral aneurysms coil embolization; Edovascular treatment; Drability of small cerebral aneurysm coil embolization; Target Nano coils

MeSH Terms

Follow-Up Studies
Humans
Intracranial Aneurysm*
Neck
Recurrence*
Retreatment

Figure

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  Fig. 1 Left SCA unruptured aneurysm (2.3 × 3.1 mm) of 63 year old female. Pre-procedural images of Angiography, white arrow (A) and three dimensionally reconstructed image (B) are shown. Aneurysm is being treated via wire assisted embolization (C, D) and partially coiled (E). 30 months follow up brain MR angiography shows complete embolization, red arrow (F).

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  Fig. 2 Right M1 unruptured aneurysm (2.0 × 1.8 mm) of 76 year of female. Pre-procedural images of computed tomography angiogram, white arrow (A) and three dimensionally reconstructed angiography (B) are shown. Aneurysm is being treated with partial embolization (C) and 4.5 years follow up brain magnetic resonance angiography shows complete embolization, red arrow (D).

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