Int Neurourol J.  2018 Sep;22(3):192-199. 10.5213/inj.1836084.042.

Factors Influencing Lower Urinary Tract Symptoms in Advanced Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy

  • 1Department of Nursing, College of Nursing and Health, Kongju National University, Gongju, Korea.
  • 2College of Nursing, The Catholic University of Korea, Seoul, Korea.
  • 3Department of Urology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea.
  • 4Department of Nursing, Seoul St. Mary's Hospital, Seoul, Korea.
  • 5Department of Nursing, Suwon Science College, Hwaseong, Korea.


This study aimed to investigate the severity of lower urinary tract symptoms (LUTS) and to identify factors that influenced LUTS in advanced cancer patients with chemotherapy-induced peripheral neuropathy (CIPN).
This cross-sectional study included a total of 158 advanced cancer patients with CIPN. A structured questionnaire including the International Prostate Symptom Score and the Functional Assessment of Cancer Therapy/Gynecology Oncology Group/Neurotoxicity scale was used. Data were analyzed using the Pearson correlation coefficient and multiple regression analysis.
Nocturia was the most prevalent LUTS. A positive relationship was found between CIPN symptoms and LUTS. The duration of cancer diagnosis and the severity of CIPN were key factors that influenced LUTS.
The severity of CIPN symptoms was the most important predictor of LUTS. Nurses' care for advanced cancer patients should incorporate a comprehensive health assessment, which includes a history of treatment and physical neuropathic symptoms, for any patient complaining of CIPN symptoms.


Neoplasm metastasis; Patients; Peripheral neuropathy; Lower urinary tract symptomsy
Full Text Links
  • INJ
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: