Nat Prod Sci.  2018 Sep;24(3):213-218. 10.20307/nps.2018.24.3.213.

A New Flavonol Glycoside from Tristemma hirtum (Melastomataceae)

Affiliations
  • 1Department of Chemistry, Faculty of Science, University of Dschang, Box 67, Dschang, Cameroon. tapondjou2001@yahoo.fr
  • 2Johannes Gutenberg University Mainz, Institute of Organic Chemistry, Duesbergweg 10-14, D-55128 Mainz, Germany.
  • 3Department of Pharmaceutical Engineering, Sangji University, 26339 Wonju, Korea. tapondjou2001@yahoo.fr

Abstract

Chemical investigation of the plant Tristemma hirtum P. Beauv (Melastomataceae) resulted to the isolation of a new flavonol glycoside named quercetin-7-O-α-D-arabinofuranoside (1), together with nine known compounds including 3"²-hexadecanoyl-2"²-(9aZ)-tetradecanoyl-glycerol 1"²-O-[β-D-galactopyranosyl-(1"³â†’ 6"³)-α-D-galactopyranoside] (2), arjunolic acid (3), β-sitosterol-3-O-β-D-glucopyranoside (4), terminolic acid (5), quercetin (6), asiatic acid (7), maslinic acid (8), 1β-O-galloylpedunculagin (9) and 6-hydroxyapigenin 7-O-β-D-glucopyranoside (10) from the methanol extract using normal and reversed phase column chromatography. The structures of these compounds were determined by comprehensive interpretation of their spectral data mainly including 1D- 2D-NMR (¹H-¹H COSY, HSQC, and HMBC) spectroscopic and ESI-TOF-MS mass spectrometric analysis.

Keyword

Tristemma hirtum; Melastomataceae; flavonol glycoside

MeSH Terms

Chromatography
Melastomataceae
Methanol
Plants
Quercetin
Methanol
Quercetin

Figure

  • Fig. 1. Chemical structures of compounds isolated from T. hirtum.

  • Fig. 2. Selected HMBC and COSY 1 H-1 H correlations of compound 1.


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