Investig Magn Reson Imaging.  2018 Sep;22(3):200-203. 10.13104/imri.2018.22.3.200.

A Case of Metronidazole-Induced Encephalopathy: Atypical Involvement of the Brain on MRI

• Hwang E
• Chang SK
• Lee SA
• Choi JA

• KMID: 2421554
• DOI: http://doi.org/10.13104/imri.2018.22.3.200

Abstract

Metronidazole is an antimicrobial agent widely used for the treatment of anaerobic infection or antibiotics-associated diarrhea. It is generally thought to be safe, but can induce reversible toxic encephalopathy in the case of excessive or cumulative over-dose. Metronidazole-induced encephalopathy generally demonstrates the characteristic features of typical lesion location and bilaterality on magnetic resonance imaging (MRI). We report a case of metronidazole-induced encephalopathy with the involvement of asymmetric white matter. To our knowledge, only a few cases have been reported with respect to white matter lesion characteristics on MRI with diffusion-weighted images.

Keyword

Metronidazole; White matter abnormality; Magnetic resonance imaging

MeSH Terms

Brain Diseases*
Brain*
Diarrhea
Magnetic Resonance Imaging*
Metronidazole
Neurotoxicity Syndromes
White Matter
Metronidazole