Imaging Sci Dent.  2018 Sep;48(3):161-165. 10.5624/isd.2018.48.3.161.

Usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases

• Ogura I
• Nakahara K
• Sasaki Y
• Sue M
• Oda T

• KMID: 2420543
• DOI: http://doi.org/10.5624/isd.2018.48.3.161

Abstract

PURPOSE
To evaluate the usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases.
MATERIALS AND METHODS
Ten patients with oral and maxillofacial diseases and 28 volunteers drawn from our student doctors were examined by shear wave elastography with a 14-MHz linear transducer using an Aplio 300 apparatus (Canon Medical Systems, Otawara, Japan). A statistical analysis of the shear elastic modulus (kPa) of healthy tissue (the sublingual gland, submandibular gland, anterior belly of the digastric muscle, and geniohyoid muscle) in the 28 volunteers was performed using 1-way repeated measures analysis of variance with the Tukey honest significant difference test. The maximum shear elastic modulus (kPa) of 8 patients with squamous cell carcinoma (SCC) and 2 patients with benign lesions was evaluated with the Mann-Whitney U test. The analysis used a 5% significance level.
RESULTS
The mean shear elastic modulus of the sublingual gland (9.4±3.7 kPa) was lower than that of the geniohyoid muscle (19.2±9.2 kPa, P=.000) and the anterior belly of the digastric muscle (15.3±6.1 kPa, P=.004). The maximum shear elastic modulus of the SCCs (109.6±14.4 kPa) was higher than that of the benign lesions (46.4±26.8 kPa, P=.044).
CONCLUSION
Our results demonstrated the usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases. Shear wave elastography has the potential to be an effective technique for the objective and quantitative diagnosis of oral and maxillofacial diseases.

Keyword

Neck; Carcinoma, Squamous Cell; Elasticity Imaging Techniques; Ultrasonography

MeSH Terms

Carcinoma, Squamous Cell
Diagnosis*
Elastic Modulus
Elasticity Imaging Techniques*
Humans
Neck
Sublingual Gland
Submandibular Gland
Transducers
Ultrasonography
Volunteers

Figure

• 

  Fig. 1 Ultrasonograms of a pleomorphic adenoma of the left submandibular gland in an 84-year-old man. A. The lesion shows clear boundaries and is isoechoic and heterogeneous, with vascular signals within the lesion. B. T1 (65.3 kPa), T2 (20.0 kPa), T3 (34.1 kPa), and T4 (29.8 kPa) show the shear elastic modulus values of this submandibular gland tumor.

• 

  Fig. 2 Ultrasonograms of a squamous cell carcinoma on the right side of the buccal mucosa in a 56-year-old man. A. The lesion shows unclear boundaries, and is isoechoic and heterogeneous, with vascular signals within the lesion. B. T1 (64.3 kPa), T2 (122.2 kPa), T3 (93.9 kPa), and T4 (63.8 kPa) show the shear elastic modulus values of this buccal mucosal tumor.

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