World J Mens Health.  2018 May;36(2):147-152. 10.5534/wjmh.17030.

Which Exercise Is Better for Increasing Serum Testosterone Levels in Patients with Erectile Dysfunction?

Affiliations
  • 1Department of Urology, Inje University Seoul Paik Hospital, Seoul, Korea. uromgpark@gmail.com
  • 2Department of Orthopedic Surgery, Konkuk University Medical Center, Seoul, Korea.
  • 3Department of Preventive Medicine, Gachon University College of Medicine, Incheon, Korea.
  • 4Department of Urology, Inje University Ilsan Paik Hospital, Goyang, Korea.
  • 5Department of Orthopedic Surgery and Sports Medical Center, Inje University Seoul Paik Hospital, Seoul, Korea.
  • 6Department of Urology, Dongguk University Ilsan Hospital, Goyang, Korea.

Abstract

PURPOSE
We investigated the correlations of serum total testosterone (TT) levels with body composition and physical fitness parameters in patients with erectile dysfunction (ED) to know the best exercise for testosterone deficiency.
MATERIALS AND METHODS
Eighty-seven ED patients underwent serum TT assessment as well as body composition and basic exercise testing. The bioelectrical impedance analysis was used to assess body composition. Seven types of basic exercise tests were used to determine physical fitness. Correlations between serum TT levels and body composition/physical function parameters were evaluated using partial correlation analyses. A serum TT cut-off value was obtained for the parameters significantly correlated with serum TT levels.
RESULTS
The subjects had a mean serum TT level of 342.1 ng/dL. Among the body composition parameters, body and abdominal fat percentages showed statistically significant negative correlations with serum TT levels. Among the basic exercise test parameters, only the cycle ergometer test for cardiorespiratory fitness showed a statistically significant positive correlation with serum TT levels.
CONCLUSIONS
Serum TT levels in patients with ED, may be increased by reducing fat percentage and improving cardiorespiratory fitness via aerobic exercise.

Keyword

Body composition; Erectile dysfunction; Exercise; Physical fitness; Testosterone

MeSH Terms

Abdominal Fat
Body Composition
Electric Impedance
Erectile Dysfunction*
Exercise
Exercise Test
Humans
Male
Physical Fitness
Testosterone*
Testosterone

Figure

  • Fig. 1 Basic exercise testing to evaluate individual physical fitness: (A) cardiorespiratory fitness by cycle ergometer test; (B) flexibility by sit-and-reach test; (C) muscular endurance by curl-up test; (D) muscular strength by grip test; (E) agility by whole body reaction test; and (F) balance by one-leg stance test.


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Reference

1. Cho DY, Yeo JK, Cho SI, Jung JE, Yang SJ, Kong DH, et al. Exercise improves the effects of testosterone replacement therapy and the durability of response after cessation of treatment: a pilot randomized controlled trial. Asian J Androl. 2017; 19:602–607. PMID: 27427553.
Article
2. Häkkinen K, Pakarinen A, Newton RU, Kraemer WJ. Acute hormone responses to heavy resistance lower and upper extremity exercise in young versus old men. Eur J Appl Physiol Occup Physiol. 1998; 77:312–319. PMID: 9562359.
3. Linnamo V, Pakarinen A, Komi PV, Kraemer WJ, Häkkinen K. Acute hormonal responses to submaximal and maximal heavy resistance and explosive exercises in men and women. J Strength Cond Res. 2005; 19:566–571. PMID: 16095404.
Article
4. Kraemer WJ, Marchitelli L, Gordon SE, Harman E, Dziados JE, Mello R, et al. Hormonal and growth factor responses to heavy resistance exercise protocols. J Appl Physiol (1985). 1990; 69:1442–1450. PMID: 2262468.
Article
5. Häkkinen K, Pakarinen A, Kraemer WJ, Newton RU, Alen M. Basal concentrations and acute responses of serum hormones and strength development during heavy resistance training in middle-aged and elderly men and women. J Gerontol A Biol Sci Med Sci. 2000; 55:B95–B105. PMID: 10737684.
6. Smilios I, Pilianidis T, Karamouzis M, Tokmakidis SP. Hormonal responses after various resistance exercise protocols. Med Sci Sports Exerc. 2003; 35:644–654. PMID: 12673149.
Article
7. Heufelder AE, Saad F, Bunck MC, Gooren L. Fifty-two-week treatment with diet and exercise plus transdermal testosterone reverses the metabolic syndrome and improves glycemic control in men with newly diagnosed type 2 diabetes and subnormal plasma testosterone. J Androl. 2009; 30:726–733. PMID: 19578132.
Article
8. Kumagai H, Zempo-Miyaki A, Yoshikawa T, Tsujimoto T, Tanaka K, Maeda S. Lifestyle modification increases serum testosterone level and decrease central blood pressure in overweight and obese men. Endocr J. 2015; 62:423–430. PMID: 25753766.
Article
9. Sajjadian F, Roshangar L, Hemmati A, Nori M, Soleimani-Rad S, Soleimani-Rad J. The effect of BSO-induced oxidative stress on histologic feature of testis: testosterone secretion and semen parameters in mice. Iran J Basic Med Sci. 2014; 17:606–612. PMID: 25422755.
10. Chigurupati S, Son TG, Hyun DH, Lathia JD, Mughal MR, Savell J, et al. Lifelong running reduces oxidative stress and degenerative changes in the testes of mice. J Endocrinol. 2008; 199:333–341. PMID: 18701639.
Article
11. Lee HK, Lee JK, Cho B. The role of androgen in the adipose tissue of males. World J Mens Health. 2013; 31:136–140. PMID: 24044108.
Article
12. Aizawa K, Iemitsu M, Maeda S, Mesaki N, Ushida T, Akimoto T. Endurance exercise training enhances local sex steroidogenesis in skeletal muscle. Med Sci Sports Exerc. 2011; 43:2072–2080. PMID: 21502890.
Article
13. Sato K, Iemitsu M, Aizawa K, Mesaki N, Fujita S. Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats. Am J Physiol Endocrinol Metab. 2011; 301:E274–E280. PMID: 21285401.
Article
14. Hehemann MC, Kashanian JA. Can lifestyle modification affect men’s erectile function. Transl Androl Urol. 2016; 5:187–194. PMID: 27141445.
Article
15. Whaley MH, Brubaker PH, Otto RM, Armstrong LE. ACSM's Guidelines for exercise testing and prescription. 7th ed. Philadelphia: Lippincott Willians & Wilkins;2006.
16. Khoo J, Tian HH, Tan B, Chew K, Ng CS, Leong D, et al. Comparing effects of low- and high-volume moderate-intensity exercise on sexual function and testosterone in obese men. J Sex Med. 2013; 10:1823–1832. PMID: 23635309.
Article
17. Hayes LD, Herbert P, Sculthorpe NF, Grace FM. Exercise training improves free testosterone in lifelong sedentary aging men. Endocr Connect. 2017; 6:306–310. PMID: 28515052.
Article
18. Zitzmann M, Faber S, Nieschlag E. Association of specific symptoms and metabolic risks with serum testosterone in older men. J Clin Endocrinol Metab. 2006; 91:4335–4343. PMID: 16926258.
Article
19. Corona G, Vignozzi L, Sforza A, Maggi M. Risks and benefits of late onset hypogonadism treatment: an expert opinion. World J Mens Health. 2013; 31:103–125. PMID: 24044106.
Article
20. Saad F, Yassin A, Haider A, Doros G, Gooren L. Elderly men over 65 years of age with late-onset hypogonadism benefit as much from testosterone treatment as do younger men. Korean J Urol. 2015; 56:310–317. PMID: 25874045.
Article
21. Hamada Y. Objective Data Assessment (ODA) methods as nutritional assessment tools. J Med Invest. 2015; 62:119–122. PMID: 26399333.
Article
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