Yonsei Med J.  2017 Jul;58(4):816-822. 10.3349/ymj.2017.58.4.816.

Factors Associated with Emotional Distress in Children and Adolescents during Early Treatment for Cancer

Affiliations
  • 1Division of Child and Adolescent Psychiatry, Department of Psychiatry, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Korea. kacheon@yuhs.ac
  • 2Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 3Division of Pediatric Hematology and Oncology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. cj@yuhs.ac

Abstract

PURPOSE
Children and adolescents diagnosed with cancer experience emotional distress, such as sadness, worrying, and irritability. However, there is little information about the psychological well-being of parents at the time of their child's diagnosis. We sought to identify factors that were associated with emotional distress in cancer patients as a basis for developing innovative psychological interventions.
MATERIALS AND METHODS
A retrospective chart review was performed on patients newly diagnosed with cancer at a single center in Korea from 2014 to 2016. Eighty-five patients and their mothers completed psychological inventories. To determine factors associated with emotional distress in patients, we assessed the psychological inventory results using multiple linear regression after performing correlation analysis.
RESULTS
The maternal Beck Depression Inventory-II (BDI-II) score was positively correlated with total problem scores and externalizing scores in patients aged less than 7 years. In patients aged 7-12 years, there was no significant association between the patient's emotional distress and other variables. In contrast, the maternal BDI-II score was the strongest factor associated with patient depression in adolescents.
CONCLUSION
We suggest that the most important factor affecting emotional distress in children and adolescents with cancer is maternal depression, especially in patients aged 1-6 years and aged 13-17 years. Understanding the factors associated with emotional distress of cancer patients allows us to develop early psychiatric interventions for patients and their parents at the initial psychological crisis.

Keyword

Diagnosis of cancer; depression; anxiety; mother-child relationship

MeSH Terms

Adolescent
Child
Child, Preschool
Demography
Female
Humans
Infant
Linear Models
Male
Neoplasms/*psychology/*therapy
Parents/psychology
Republic of Korea
Retrospective Studies
Stress, Psychological/*complications

Figure

  • Fig. 1 Correlations between maternal BDI-II score and K-CBCL score of patients aged 1–6 years. (A) Scatter plot showing a significant positive correlation between maternal BDI-II score and patient total problem score (p<0.01, r=0.373, n=47). (B) Scatter plot showing lack of correlation between maternal BDI-II score and patient internalizing score (p=0.11, r=0.239, n=47). (C) Scatter plot showing a significant positive correlation between maternal BDI-II score and patient externalizing score (p<0.05, r=0.311, n=47). Comparisons were made using the Pearson correlation. Each point represents an individual patient. BDI-II, Beck Depression Inventory-II; K-CBCL, Korean-Child Behavior Checklist.

  • Fig. 2 Correlation between maternal BDI-II score and CDI score of patients aged 7–12 years. Scatter plot showing lack of correlation between maternal BDI-II score and patient CDI score (p=0.99, r=0.00, n=13). Comparisons were made using the Pearson correlation. Each point represents an individual patient. BDI-II, Beck Depression Inventory-II; CDI, Children's Depression Inventory.

  • Fig. 3 Correlation between maternal BDI-II score and BDI-II score of patients aged 13–17 years. Scatter plot showing a significant positive correlation between maternal BDI-II score and patient BDI-II score (p<0.01, r=0.595, n=25). Comparisons were made using the Pearson correlation. Each point represents an individual patient. BDI-II, Beck Depression Inventory-II.


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