Ann Pediatr Endocrinol Metab.  2018 Jun;23(2):99-102. 10.6065/apem.2018.23.2.99.

Association Kikuchi disease with Hashimoto thyroiditis: a case report and literature review

• Lee EJ
• Lee HS
• Park JE
• Hwang JS

• KMID: 2417767
• DOI: http://doi.org/10.6065/apem.2018.23.2.99

Abstract

Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disease characterized by fever and lymphadenopathy. The etiology of KFD is unknown, but an autoimmune cause has been suggested. Hashimoto thyroiditis is the most common autoimmune thyroid disorder in children and is known to be associated with other autoimmune diseases. Only a few cases of Hashimoto thyroiditis associated with KFD have been documented. We report a case of a 16-year-old girl who was first diagnosed with KFD and developed Hashimoto thyroiditis 2 years and 6 months later during her follow-up period. Physicians of patients with KFD should consider the possibility of autoimmune diseases like Hashimoto's thyroiditis.

Keyword

Kikuchi-Fujimoto disease; Hashimoto thyroiditis; Autoimmune disease

MeSH Terms

Adolescent
Autoimmune Diseases
Child
Female
Fever
Follow-Up Studies
Hashimoto Disease*
Histiocytic Necrotizing Lymphadenitis*
Humans
Lymphatic Diseases
Thyroid Gland
Thyroiditis

Figure

• 

  Fig. 1. Axial contrast-enhanced computed tomography of the neck show multiple heterogeneous enlarged lymph nodes in both neck. The maximum size of the lymph nodes in both neck at levels II (A; arrow) and IV (B).

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