Intest Res.  2018 Apr;16(2):168-177. 10.5217/ir.2018.16.2.168.

Predicting outcomes to optimize disease management in inflammatory bowel disease in Japan: their differences and similarities to Western countries

• Kobayashi
• Hisamatsu
• Suzuki Y
• Ogata H
• Andoh A
• Araki T
• Hokari R
• Iijima H
• Ikeuchi H
• Ishiguro Y
• Kato S
• Kunisaki R
• Matsumoto
• Motoya S
• Nagahori M
• Nakamura S
• Nakase H
• Tsujikawa
• Sasaki M
• Yokoyama K
• Yoshimura
• Watanabe K
• Katafuchi
• Watanabe M
• Hibi T

• KMID: 2417669
• DOI: http://doi.org/10.5217/ir.2018.16.2.168

Abstract

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disease of the gastrointestinal tract, with increasing prevalence worldwide. IBD Ahead is an international educational program that aims to explore questions commonly raised by clinicians about various areas of IBD care and to consolidate available published evidence and expert opinion into a consensus for the optimization of IBD management. Given differences in the epidemiology, clinical and genetic characteristics, management, and prognosis of IBD between patients in Japan and the rest of the world, this statement was formulated as the result of literature reviews and discussions among Japanese experts as part of the IBD Ahead program to consolidate statements of factors for disease prognosis in IBD. Evidence levels were assigned to summary statements in the following categories: disease progression in CD and UC; surgery, hospitalization, intestinal failure, and permanent stoma in CD; acute severe UC; colectomy in UC; and colorectal carcinoma and dysplasia in IBD. The goal is that this statement can aid in the optimization of the treatment strategy for Japanese patients with IBD and help identify high-risk patients that require early intervention, to provide a better long-term prognosis in these patients.

Keyword

Crohn disease; Colitis, ulcerative; Prognosis; Colorectal neoplasms; Consensus

MeSH Terms

Asian Continental Ancestry Group
Colectomy
Colitis, Ulcerative
Colorectal Neoplasms
Consensus
Crohn Disease
Disease Management*
Disease Progression
Early Intervention (Education)
Epidemiology
Expert Testimony
Gastrointestinal Tract
Hospitalization
Humans
Inflammatory Bowel Diseases*
Japan*
Prevalence
Prognosis

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