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J Korean Med Sci.  2017 Jan;32(1):151-154. 10.3346/jkms.2017.32.1.151.

Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak

Affiliations
  • 1Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. collacin@hotmail.com
  • 2Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

A case-control study was performed to identify clinical predictors for Middle East respiratory syndrome coronavirus (MERS-CoV) infection among patients with acute febrile illness during the nosocomial outbreak. Patients with MERS-CoV were more likely to have monocytosis with normal white blood cell (WBC) count and lower C-reactive protein (CRP) level. Simple laboratory data such as complete blood counts (CBC) with differential count could be a useful marker for the prediction of MERS and triage at the initial presentation of acute febrile patients in outbreak setting.

Keyword

Middle East Respiratory Syndrome; Coronavirus; Predictors; Monocytosis

MeSH Terms

Blood Cell Count
C-Reactive Protein
Case-Control Studies
Cell Count*
Coronavirus
Coronavirus Infections*
Humans
Leukocytes
Middle East Respiratory Syndrome Coronavirus*
Middle East*
Triage
C-Reactive Protein
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