J Korean Med Sci.
2018 Jun;33(24):e169. 10.3346/jkms.2018.33.e169.
Correlation between Pneumonia Severity and Pulmonary Complications in Middle East Respiratory Syndrome
- Park WB
- Jun KI
- Kim G
- Choi JP
- Rhee JY
- Cheon S
- Lee CH
- Park JS
- Kim Y
- Joh JS
- Chin BS
- Choe PG
- Bang JH
- Park SW
- Kim NJ
- Lim DG
- Kim YS
- Oh MD
- Shin HS
- Affiliations
-
- 1Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
- 2Center for Infectious Diseases, National Medical Center, Seoul, Korea. hyoungsshin@nmc.or.kr
- 3Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.
- 4Division of Infectious Disease, Department of Medicine, Dankook University College of Medicine, Cheonan, Korea.
- 5Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea.
- 6Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
- 7Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.
- 8Infectious Diseases Research Center, Research Institute, National Medical Center, Seoul, Korea.
- 9Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Medical Center, Seoul, Korea.
- KMID: 2413720
- DOI: http://doi.org/10.3346/jkms.2018.33.e169
Abstract
- This nationwide, prospective cohort study evaluated pulmonary function and radiological sequelae according to infection severity in 73 survivors from the 2015 Middle East respiratory syndrome (MERS) outbreak in Korea. Patients with severe pneumonia in MERS-coronavirus infection had more impaired pulmonary function than those with no or mild pneumonia at the 1-year follow-up, which was compatible with the radiological sequelae. Severe pneumonia significantly impairs pulmonary function and makes long radiological sequelae in MERS.
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