Korean J Thorac Cardiovasc Surg.  2018 Feb;51(1):22-28. 10.5090/kjtcs.2018.51.1.22.

Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center

• Jeong YH
• Choi S
• Park SI
• Kim DK
• Asan Medical Center Lung Transplantation Team

• KMID: 2409709
• DOI: http://doi.org/10.5090/kjtcs.2018.51.1.22

Abstract

BACKGROUND
Lung transplantation is a life-saving procedure in patients with end-stage lung disease, and is increasingly performed in Korea.
METHODS
We retrospectively evaluated the outcomes of patients who received a lung transplant at Asan Medical Center between January 2008 and December 2016. Thirteen of 54 patients experienced multiorgan transplantation; the remaining 41 who received only lung grafts were included.
RESULTS
The mean age of the lung transplant recipients was 44.6 years; 27 were men and 14 were women. The most frequent reasons were idiopathic interstitial pneumonia (21 of 41 patients, 51.2%), interstitial lung disease (9 of 41, 22.0%), and bronchiolitis obliterans after bone marrow transplantation (7 of 41, 17.1%). The median waiting time was 47 days, and many patients received preoperative intensive care (27 of 41, 65.9%), ventilator support (26 of 41, 63.4%), or extracorporeal life support (19 of 41, 46.3%). All 41 patients received bilateral lung grafts. Ten deaths occurred (24.3%), including 5 cases of early mortality (12.2%) and 5 cases of late mortality (12.2%). The 1-, 3-, and 5-year survival rates were 78.9%, 74.2%, and 69.3%, respectively.
CONCLUSION
Despite a high percentage of patients who required preoperative intensive care, the transplantation outcomes were acceptable.

Keyword

Lung transplantation; Extracorporeal membrane oxygenation (ECMO); Survival

MeSH Terms

Bone Marrow Transplantation
Bronchiolitis Obliterans
Chungcheongnam-do*
Critical Care
Female
Humans
Idiopathic Interstitial Pneumonias
Korea
Lung Diseases
Lung Diseases, Interstitial
Lung Transplantation*
Lung*
Male
Mortality
Retrospective Studies
Survival Rate
Transplant Recipients
Transplants
Ventilators, Mechanical