Investig Magn Reson Imaging.  2018 Mar;22(1):50-55. 10.13104/imri.2018.22.1.50.

Gelatinous Transformation of Bone Marrow Mimicking Malignant Marrow-Replacing Lesion on Magnetic Resonance Imaging in a Patient without Underlying Devastating Disease

Affiliations
  • 1Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. agn70@yuhs.ac
  • 2Department of Pathology, Green Cross Laboratories, Gyeonggi-do, Korea.
  • 3Department of Orthopaedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Gelatinous transformation of bone marrow is characterized by hypoplasia of fat cells with focal loss of hematopoietic cells and deposition of extracellular gelatinous substances. It is known to be associated with devastating underlying diseases that starve bone marrow. Here, we present a case of a patient whose magnetic resonance (MR) imaging findings of vertebral column were interpreted as metastasis or hematologic malignancy, however, the final diagnosis revealed a gelatinous transformation of bone marrow. This is the first report of gelatinous transformation of bone marrow without evidence of underlying devastating disease.

Keyword

Gelatinous transformation; Bone marrow; Magnetic resonance imaging; Positron emission tomography

MeSH Terms

Adipocytes
Bone Marrow*
Diagnosis
Gelatin*
Hematologic Neoplasms
Humans
Magnetic Resonance Imaging*
Neoplasm Metastasis
Positron-Emission Tomography
Spine
Gelatin
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