J Korean Soc Radiol.  2018 Feb;78(2):130-134. 10.3348/jksr.2018.78.2.130.

Radiologic Manifestation of Intra-Abdominal Involvement of Systemic Amyloidosis Secondary to Renal Cell Carcionma

  • 1Department of Radiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea. bbr322@naver.com
  • 2Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
  • 3Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
  • 4Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.


Amyloidosis has a wide spectrum of manifestations in numerous abdominal organs. It can be categorized into primary or secondary disease according to the presence of accompanying conditions, such as rheumatoid arthritis, tuberculosis, or neoplasms. Herein, we present a rare case of amyloidosis associated with renal cell carcinoma that showed nonspecific radiologic features such as diffuse bowel wall thickening, ascites and peritoneal thickening.

MeSH Terms

Arthritis, Rheumatoid
Carcinoma, Renal Cell


  • Fig. 1. A 21-year-old woman of systemic amyloidosis secondary to RCC. A. Axial CT scan shows a 6 cm–sized enhancing mass (arrow) at the right kidney, suggestive of RCC and multiple metastatic lymph nodes at the aortocaval and retrocaval areas. B. Photomicrograph (× 100, hematoxylin-eosin stain) shows eosinophilic cytoplasm and sparse capillaries (arrows), Histologic diagnosis is papillary RCC. C. Photomicrograph (× 100, Congo red stain) shows strong affinity for the stain (arrow), suggestive of amyloidosis. D. Postoperative CT scan reveals diffuse wall thickening of small bowel, colon and ascites, peritoneal thickening. These findings are worse than the findings of preoperative CT scan. E. Colonoscopy image reveals scarring, redness and diffuse mucosal thickening of ascending colon and the histologic diagnosis is amyloidosis. CT = computed tomography, RCC = renal cell carcinoma



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